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One of the more common methods of using Streptavidin-ZAP is to couple the complex with biotinylated antibodies. However, there are also many instances of biotinylated ligands, peptides, and even biotinylated major histocompatibility complex (MHC) tetramers in immunology fields. B-Cell Targeting. An example of utilizing Streptavidin-ZAP to study ligands that target CD22 were shown by Collins
Saporin Uses in Immunology Read More »
NGFr (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07) The p75 neurotrophin receptor (p75NTR), also known as the low affinity nerve growth factor receptor, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NTR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective
May 12-14, Booth 5067 Molecular Surgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Visit Booth 5067, May 12-14 and find out how you can use Molecular Surgery. Curated Resources Saporin Uses in Immunology Immunology
American Association of Immunologists, AAI 2023 Read More »
April 15-19, Booth 2342 Molecular Surgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Visit Booth 2342, April 15-19 and find out how you can use Molecular Surgery to discover a cure for cancer.
American Association for Cancer Research, AACR 2023 Read More »
ATS Animal Models ATS offers many different Animal Model products and full kits for various disease and behavioral research applications. Animal Models Learn more about our Saporin-produced Animal Models. Choose the product links below for the Animal Model of your interest. Most Animal Models are ready in 2 weeks using our Saporin conjugate system to
pHast Conjugates pHast Conjugates are one of our pHastest tools for quantitative testing of your primary antibody’s specificity, binding, and internalization, providing results in 1 day. How It Works The pHast conjugate binds to your primary antibody via a secondary antibody cross-linked to a pH-dependent fluorescent reporter. This fluorescent reporter will increase intensity as the
Toolbox: pHast Conjugates Read More »
Biotin-Z Internalization Kit Screen Your Biotinylated Targeting Agent Also available in Chinese | French | German | Italian | Japanese | Korean | Portuguese | Spanish Biotin-Z Internalization Kit Explainer Whiteboard IN VITRO or IN VIVO applications provide definitive results Targeting Agents to Extracellular Markers For Example: Biotin-Z Internalization Kit Use cell surface markers to
Biotin-Z Internalization Kit Introduction Read More »
Join us at the German Neuroscience Society meeting in Göttingen! Molecular Neurosurgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Visit Booth 3, March 22-24 and find out how you can use Molecular Neurosurgery to
German Neuroscience Society – 2023 Meeting Read More »
This manuscript describes the myriad of ways Streptavidin-ZAP is used and how this technology supports the scientific process of ‘Molecular Surgery’ and progress in research and drug development. Insights from publications and research performed using Streptavidin-ZAP and its impact on academia and industry for research and drug development are presented. Read the full article as
Streptavidin-saporin: Converting biotinylated materials into targeted toxins Read More »