Have you read Targeting Trends newsletters? Now in a more convenient format, the ATS newsletters are accessible on our website. Features include summaries of the latest publications, FAQ to answer product questions, and articles with cutting edge research shared by featured scientists. Plus cameo appearances by our beloved cats. Flip through the pages of the newsletters like […]
Neuroscience 2021 and Targeting Trends Read More »
Itch Induces Conditioned Place Aversion in Mice. Mu, D, & Sun, Y-G. (2017). Neuroscience Letters, http://dx.doi.org/10.1016/j.neulet.2017.08.046 “Consistently, ablation of itch‐specific neurons that express gastrin‐releasing peptide receptor in the spinal cord also abolished itch‐induced Conditioned Place Aversion (CPA), confirming that itch‐induced CPA is dependent on the spinal itch circuit.” Mice were given a single intrathecal injection
Got an itch? Bombesin-SAP may help Read More »
Contributed by William Truitt, PhD, Department of Cell Biology, Neurobiology, and Anatomy, Neuroscience Graduate Program, University of Cincinnati, College of Medicine, Post Office Box 670521, Cincinnati, OH 45267-0521, USA. Previously we demonstrated the existence of a spinothalamic pathway in the male rat where neural activation is specifically induced by ejaculation.1 This pathway includes the parvocellular
Cover Article: Deep Lumbar Neurons Control Ejaculation Read More »
Contributed by Maria Montero (a), Berta Gonzalez (b), Jens Zimmer (a)(a) Anatomy and Neurobiology, University of Southern Denmark, Denmark(b) Histology Unit, Autonomous University of Barcelona, Spain Microglial cells contribute about 12% of the cells in the brain, acting as “biosensors” for homeostatic regulation in normal and pathological conditions.[3,13] Resting microglial cells in the adult brain
Q: I am planning an experiment to investigate the effects of ablation of spinal NK-1r-expressing cells (using intrathecal injection of SSP-SAP, Cat. #IT-11). In the first part of the experiment I want to destroy the NK-1r-expressing cells before surgical modification. I am unsure how long after injection of SSP-SAP I should carry out the surgery.
ATS Animal Models ATS offers many different Animal Model products and full kits for various disease and behavioral research applications. Animal Models Learn more about our Saporin-produced Animal Models. Choose the product links below for the Animal Model of your interest. Most Animal Models are ready in 2 weeks using our Saporin conjugate system to
NGFr (ME20.4, p75) Mouse Monoclonal (Cat. #AB-N07) The p75 neurotrophin receptor (p75NTR), also known as the low affinity nerve growth factor receptor, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. The p75NTR plays an important role in neurotrophic factor signaling and has been shown to modulate the susceptibility of selective
Come visit us at The Society for Neuroscience in Chicago – October 19-23, Booth #763. We have some exciting new products to talk to you about. Cell Transfection Kit & Service Temporal Lobe Epilepsy Animal Model
New product announcements at SfN: Transfection and Epilepsy tools Read More »
Antibody Drug Conjugates to Treat Cancer A Brief History of Saporin and its Contributions to Neuroscience Targeted Toxins – Cheaper and Quicker than Knockouts A rapid, pH-sensitive screening method to detect internalization of cell surface markers for development of antibody-based pharmaceuticals to treat brain tumors. Screening targeting agents and their cell surface biomarkers for high
Since 2000, Advanced Targeting Systems has presented an award each year at the Society for Neuroscience meeting for the best Poster of the Year using ATS targeting tools. This year the competition was fierce and some very exciting science was presented. Also, a big congratulations to the winner of the drawing for a $500 product
Poster Award goes to Orexin-B Read More »