Biotin-Z Internalization Kit Screen Your Biotinylated Targeting Agent Also available in Chinese | French | German | Italian | Japanese | Korean | Portuguese | Spanish Biotin-Z Internalization Kit Explainer Whiteboard IN VITRO or IN VIVO applications provide definitive results Targeting Agents to Extracellular Markers For Example: Biotin-Z Internalization Kit Use cell surface markers to […]
Biotin-Z Internalization Kit Introduction Read More »
Join us at the German Neuroscience Society meeting in Göttingen! Molecular Neurosurgery definition: Specifically remove cells based on a unique cell surface marker; useful in both in vitro (e.g., antibody screening) and in vivo (e.g., ‘knock out’ models, functionomics) applications. Visit Booth 3, March 22-24 and find out how you can use Molecular Neurosurgery to
German Neuroscience Society – 2023 Meeting Read More »
This manuscript describes the myriad of ways Streptavidin-ZAP is used and how this technology supports the scientific process of ‘Molecular Surgery’ and progress in research and drug development. Insights from publications and research performed using Streptavidin-ZAP and its impact on academia and industry for research and drug development are presented. Read the full article as
Streptavidin-saporin: Converting biotinylated materials into targeted toxins Read More »
192-IgG-SAP (targets NGFR+ cells) Anti-DBH-SAP (targets dopamine beta hydroxylase)
Alzheimer’s Disease Research Read More »
Summary: These results indicate a prominent role of NA-neurons vs. ACh ones in impairments of working memory, relevant for Alzheimer’s Disease. Usage: Bilateral icv injection of 192-IgG-SAP and/or Anti-DBH-SAP. G. Leanza and R. Zorec. Function 2023, 4(1) DOI: 10.1093/function/zqac060. We would be pleased to send you our 2023 ATS calendar. Click here to provide us your
Saporin Publication highlighting 192-IgG-SAP and Anti-DBH-SAP Read More »
ZAP Antibody Internalization Kit Also available in French | German | Japanese | Korean | Mandarin | Italian | Portuguese | Spanish ZAP Antibody Internalization Kit Explainer Whiteboard Browse kit options and order your kit. keywords: research, drug development, bind to cell types, ZAP Antibody Internalization Kit, screen antibodies, binding, internalization, cytotoxicity assay, specific, secondary, saporin, primary, cell surface marker, internalized
ZAP Antibody Internalization Kit Introduction Read More »
ABSTRACT When investigating the origins of targeted toxins (a drug, therapy, or scientific tool directed to unique extracellular target), an appropriate place to begin is with the Nobel Prize-winning work of Paul Ehrlich and his concept of the “magic bullet.” Over 100 years later, the use of targeted toxins to perform molecular neurosurgery has become
A Brief History of Saporin and its Contributions to Neuroscience Read More »
Read the complete 2021 Review including recent scientific references. Targeted Ablation with IB4-SAP: Selective ablation of IB4+ primary afferent neurons reduces mechanical and cold hyperalgesia in an EAE mouse model of multiple sclerosis Top 20 Targeting Tools
Targeting Trends 2021 Review Read More »
Top Five Targeted Toxins #1. CTB-SAP (Cat. #IT-14) – targets cells expressing GM1 receptor #2 Mac-1-SAP (Cat. #IT-06) – targets cells expressing Mac-1 (CD11b ) receptor #3 Anti-CD103-SAP (Cat. #IT-50) – targets cells expressing CD103 #4. Anti-DBH-SAP (Cat. #IT-03) – targets cells expressing rat dopamine beta-hydroxylase #5. mu p75-SAP (Cat. #IT-16) – targets cells expressing mouse
Top 20 Targeting Tools of 2021 Read More »