Targeting Tools: ZAP SrB Development Kit

The ZAP Sulforhodamine B (SrB; Cat. #KIT-SrB-Z) Development kit contains all of the materials needed to introduce a quantitative staining assay to your lab. Preferred by the National Cancer Institute for high-throughput drug screening, SrB quantitatively stains cellular proteins in an accurate and reproducible manner. Refined and honed over years of use in testing Saporin-conjugate

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Veterinary Development of Substance P-Saporin (SP-SAP)

A groundbreaking pain therapeutic is poised for conditional approval in 2015 to treat bone cancer pain in dogs. The FDA has already approved Minor Use/Minor Species (MUMS) designation for the drug, providing extended market exclusivity to treat the >10,000 annual cases of canine bone cancer-related pain, and the ability to commercialize the drug as soon

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Cover Article: Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in Parkinson’s Disease

by Aaron Kucinski (Collaborators at University Michigan, Ann Arbor: K. Phillips, R. Albin, M. Sarter) In addition to the primary disease-defining symptoms that result from extensive loss of nigrostriatal dopaminergic neurons, approximately half of patients with Parkinson’s Disease (PD) suffer from postural instability, impairments in gait control and a propensity for falls. These symptoms have

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SFN Poster of the Year 2014

Congratulations to this year’s winner of ATS’ Poster of the Year featuring IT-42 Anti-ChAT-SAP. Be sure to check out the featured article in Targeting Trends. 692.21 Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in PDK Phillips, A Kucinski, R Albin, M Sarterfeaturing IT-42 Anti-ChAT-SAP (poster; Wednesday, Nov. 19,

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Targeting Tools: Beta Testing Program

ATS is pleased to announce Beta-release of a wide array of targeted toxins for use in eliminating specific cell types. This Beta-Testing Program will make new conjugates available to our customers sooner. Each of the Beta products will have: Saporin activity confirmed, Peptide sequences published/confirmed, and/or Antibody binding specificity published/confirmed. Beta Products have not been

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