Loss of leptin receptor-expressing cells in the hindbrain decreases forebrain leptin sensitivity.
Harris RBS (2020) Loss of leptin receptor-expressing cells in the hindbrain decreases forebrain leptin sensitivity. Am J Physiol Endocrinol Metab 318(5):E806-E816. doi: 10.1152/ajpendo.00020.2020 Objective: This study tested whether loss of hindbrain leptin receptor signaling changed sensitivity to forebrain leptin. Summary: Loss of VMH (ventromedial nucleus of hippocampus) leptin receptor-expressing cells prevents weight loss. The integrated […]