He X, Long Q, Zeng Z, Yang L, Tang Y, Feng X (2019) Simple and efficient targeted intracellular protein delivery with self-assembled nanovehicles for effective cancer therapy. Adv Funct Mater 29(50):1906187. doi: 10.1002/adfm.201906187 Related Products: Saporin (Cat. #PR-01)
Murillo-Rodríguez E, Millán-Aldaco D, Palomero-Rivero M, Morales-Lara D, Mechoulam R, Drucker-Colín R (2019) Cannabidiol partially blocks the excessive sleepiness in hypocretindeficient rats: Preliminary data. CNS Neurol Disord Drug Targets 18(9):705-712. doi: 10.2174/1871527318666191021143300 Objective: To determine whether the systemic injection of CBD (5 mg/kg, i.p.) would block the excessive sleepiness in a narcoleptic model. Summary: Preliminary
Verkhratsky A, Parpura V, Rodriguez-Arellano J, Zorec R (2019) Astroglia in Alzheimer’s Disease. (eds. Verkhratsky A, Ho M, Zorec R, Parpura V). In: Advances in Experimental Medicine and Biology: Neuroglia in Neurodegenerative Diseases. 1175:273-324. Springer, Singapore. doi: 10.1007/978-981-13-9913-8_11 Summary: A review of the tools for creating animal models of Alzheimer’s Disease. 192-IgG-SAP binds selectively and
Astroglia in Alzheimer’s Disease. Read More »
Klotz L, Wendler O, Frischknecht R, Shigemoto R, Schulze H, Enz R (2019) Localization of group II and III metabotropic glutamate receptors at pre- and postsynaptic sites of inner hair cell ribbon synapses. FASEB J 33(12):13734-13746. doi: 10.1096/fj.201901543R PMID: 31585509 Usage: immunohistochemistry (1:150) Related Products: Metabotropic Glutamate Receptor 2 (mGluR2) Mouse Monoclonal (Cat. #AB-N32)
Martins JR, Reichhart N, Kociok N, Stindl J, Foeckler R, Lachmann P, Todorov V, Castrop H, Strauß O (2019) Systemic ß adrenergic stimulation/ sympathetic nerve system stimulation influences intraocular RAS through cAMP in the RPE. Exp Eye Res 189:107828. doi: 10.1016/j.exer.2019.107828 PMID: 31589840 Objective: To investigate whether systemic β-adrenergic stimulation of the retinal pigment epithelium
Fab-pHast products bind to your primary antibody via a secondary antibody or Streptavidin cross-linked to a pH-dependent fluorescent reporter. This fluorescent reporter increases intensity as the pH of its surroundings becomes more acidic, as evident when exposed to the environment inside a cell. SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked
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Seamon M, Ahn W, Li AJ, Ritter S, Harris RBS (2019) Leptin receptor-expressing neurons in ventromedial nucleus of the hypothalamus contribute to weight loss caused by fourth ventricle leptin infusions. Am J Physiol Endocrinol Metab 317(4):E586-E596. doi: 10.1152/ajpendo.00205.2019 Objective: To test the importance of VMH leptin responsiveness in mediating weight loss caused by fourth ventricle
Phillips K (2019) Micro- and macro-psychological analyses of attention and the role of cholinergic systems. University of Michigan Thesis. doi: 2027.42/151673 Objective: To determine the validity of behavioral tasks used to reveal neurobehavioral and neurocognitive mechanisms of attention. Summary: The opposing cognitive-motivational styles of sign-trackers and goal-trackers, while originating in different approaches to food and
Micro- and macro-psychological analyses of attention and the role of cholinergic systems Read More »
Pan H, Fatima M, Li A, Lee H, Cai W, Horwitz L, Hor CC, Zaher N, Cin M, Slade H, Huang T, Xu XZS, Duan B (2019) Identification of a spinal circuit for mechanical and persistent spontaneous itch. Neuron 103(6):1135-1149.e6. doi: 10.1016/j.neuron.2019.06.016 Objective: To identify a spinal circuit for mechanical and persistent spontaneous itch. Summary:
Identification of a spinal circuit for mechanical and persistent spontaneous itch. Read More »
Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q (2019) Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice. Blood Adv 3(18):2700-2711. doi: 10.1182/bloodadvances.2019000516 Objective: To determine whether hematopoietic cell–targeted ADC preconditioning is effective for engraftments