Author name: Kristen Hartman

Central glucagon-like peptide-1 receptor signaling via brainstem catecholamine neurons counteracts hypertension in spontaneously hypertensive rats.

Katsurada K, Nakata M, Saito T, Zhang B, Maejima Y, Nandi SS, Sharma NM, Patel KP, Kario K, Yada T (2019) Central glucagon-like peptide-1 receptor signaling via brainstem catecholamine neurons counteracts hypertension in spontaneously hypertensive rats. Sci Rep 9(1):12986. doi: 10.1038/s41598-019-49364-x Objective: To determine mechanisms for antihypertensive effect of GLP-1R agonists. Summary: The central GLP-1R […]

Central glucagon-like peptide-1 receptor signaling via brainstem catecholamine neurons counteracts hypertension in spontaneously hypertensive rats. Read More »

LncRNA AK094457 promotes AngII-mediated hypertension and endothelial dysfunction through suppressing of activation of PPARγ.

Zhuo X, Wu Y, Yang Y, Gao L, Qiao X, Chen T (2019) LncRNA AK094457 promotes AngII-mediated hypertension and endothelial dysfunction through suppressing of activation of PPARγ. Life Sci 233:116745. doi: 10.1016/j.lfs.2019.116745 PMID: 31404524 Objective: To find the functional lncRNAs associated with hypertension, high throughput lncRNA microarray were used to analyze expression profile of the

LncRNA AK094457 promotes AngII-mediated hypertension and endothelial dysfunction through suppressing of activation of PPARγ. Read More »

Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer’s disease.

Veening-Griffioen DH, Ferreira GS, van Meer PJK, Boon WPC, Gispen-de Wied CC, Moors EHM, Schellekens H (2019) Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer’s disease. Eur J Pharmacol 859:172524. doi: 10.1016/j.ejphar.2019.172524 Related Products: 192-IgG-SAP (Cat. #IT-01)

Are some animal models more equal than others? A case study on the translational value of animal models of efficacy for Alzheimer’s disease. Read More »

Enteric apelin enhances the stress-induced stimulation of colonic motor functions.

Bülbül M, Sinen O, Bayramoğlu O, Akkoyunlu G (2019) Enteric apelin enhances the stress-induced stimulation of colonic motor functions. Stress 23(2):201-212. doi: 10.1080/10253890.2019.1658739 PMID: 31441348 Usage: histology (1:100) Related Products: Corticotropin Releasing Hormone Rabbit Polyclonal (Cat. #AB-02)

Enteric apelin enhances the stress-induced stimulation of colonic motor functions. Read More »

Development of intestinal scaffolds that mimic native mammalian intestinal tissue

Ladd MR, Costello CM, Gosztyla C, Werts AD, Johnson B, Fulton WB, Martin LY, Redfield EJ, Crawford B, Panaparambil R, Sodhi CP, March JC, Hackam DJ (2019) Development of intestinal scaffolds that mimic native mammalian intestinal tissue. Tissue Eng Part A 25(17-18):1225-1241. doi: 10.1089/ten.TEA.2018.0239 PMID: 30652526 Objective: To develop a scaffold for the generation of

Development of intestinal scaffolds that mimic native mammalian intestinal tissue Read More »

Metalloprotease inhibitor timp proteins control FGF-2 bioavailability and regulate skeletal growth.

Saw S, Aiken A, Fang H, McKee TD, Bregant S, Sanchez O, Chen Y, Weiss A, Dickson BC, Czarny B, Sinha A, Fosang A, Dive V, Waterhouse PD, Kislinger T, Khokha R (2019) Metalloprotease inhibitor timp proteins control FGF-2 bioavailability and regulate skeletal growth. J Cell Biol 218(9):3134-3152. doi: 10.1083/jcb.201906059 PMID: 31371388 Usage: immunostaining (1:100)

Metalloprotease inhibitor timp proteins control FGF-2 bioavailability and regulate skeletal growth. Read More »

Lesions of the patch compartment of dorsolateral striatum disrupt stimulus-response learning.

Jenrette TA, Logue JB, Horner KA (2019) Lesions of the patch compartment of dorsolateral striatum disrupt stimulus-response learning. Neuroscience 415:161-172. doi: 10.1016/j.neuroscience.2019.07.033 Objective: To investigate whether enhanced activation of the patch compartment contributes to habitual behavior. Summary: The dorsolateral patch compartment may mediate habit formation by altering information flow through basal ganglia circuits. Usage: A

Lesions of the patch compartment of dorsolateral striatum disrupt stimulus-response learning. Read More »

Hindbrain glucoregulatory mechanisms: Critical role of catecholamine neurons in the ventrolateral medulla.

Ritter S, Li A-J, Wang Q (2019) Hindbrain glucoregulatory mechanisms: Critical role of catecholamine neurons in the ventrolateral medulla. Physiol Behav 208:112568. doi: 10.1016/j.physbeh.2019.112568 Objective: To explore circuitry and potential glucose-sensing mechanisms that contribute to the functions of glucoregulatory catecholamine neurons in the ventrolateral medulla Summary: Selective lesion of hindbrain catecholamine neurons abolishes glucoprivic elicitation

Hindbrain glucoregulatory mechanisms: Critical role of catecholamine neurons in the ventrolateral medulla. Read More »

Partial depletion of septohippocampal cholinergic cells reduces seizure susceptibility, but does not mitigate hippocampal neurodegeneration in the kainate model of epilepsy.

Soares JI, Da Costa C, Ferreira MH, Andrade PA, Maia GH, Lukoyanov NV (2019) Partial depletion of septohippocampal cholinergic cells reduces seizure susceptibility, but does not mitigate hippocampal neurodegeneration in the kainate model of epilepsy. Brain Res 1717:235-246. doi: 10.1016/j.brainres.2019.04.027 Objective: To examine how the inhibition of epilepsy-related cholinergic plasticity may be reflected in seizure

Partial depletion of septohippocampal cholinergic cells reduces seizure susceptibility, but does not mitigate hippocampal neurodegeneration in the kainate model of epilepsy. Read More »

The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats.

Maejima Y, Yokota S, Horita S, Shimomura K (2019) The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats. Sci Rep 9(1):11848. doi: 10.1038/s41598-019-48336-5 Objective: To determine the underlying mechanisms that induce high energy intake (EI) per body weight (BW). Summary: Undeveloped properties of VTA GABA

The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats. Read More »

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