Hasegawa H, Selway R, Gnoni V, Beniczky S, Williams SCR, Kryger M, Ferini-Strambi L, Goadsby P, Leschziner GD, Ashkan K, Rosenzweig I (2020) The subcortical belly of sleep: New possibilities in neuromodulation of basal ganglia?. Sleep Med Rev 52:101317. doi: 10.1016/j.smrv.2020.101317
Summary: Complete BF lesion with OX-SAP leads to coma-like state and flat EEG, reduced Fos in cerebral cortex (but high Fos in brainstem, thalamus, hypothalamus) selective (cholinergic or non-cholinergic) lesion does not have this effect.
Usage: Lesions of the basal forebrain were done by injecting a 0.1% solution of Orexin-SAP at four different sites.
Related Products: Orexin-B-SAP (Cat. #IT-20)