Author name: Kristen Hartman

Featured Article: Selective ablation of IB4+ primary afferent neurons reduces mechanical and cold hyperalgesia in an EAE mouse model of multiple sclerosis

Nguyen KL, Lamerand SR, Deshpande RP, Taylor BK (2021) Featured Article: Selective ablation of IB4+ primary afferent neurons reduces mechanical and cold hyperalgesia in an EAE mouse model of multiple sclerosis. Targeting Trends 22 Related Products: IB4-SAP (Cat. #IT-10), Blank-SAP (Cat. #IT-21) Read the featured article in Targeting Trends. See Also: Nguyen KL et al. […]

Featured Article: Selective ablation of IB4+ primary afferent neurons reduces mechanical and cold hyperalgesia in an EAE mouse model of multiple sclerosis Read More »

Top 20 Targeting Tools of 2020

News Tools /

Top Five Targeted Toxins #1. CTB-SAP  (Cat. #IT-14) – targets cells expressing GM1 receptor #2. Anti-DBH-SAP (Cat. #IT-03) – targets cells expressing rat dopamine beta-hydroxylase  #3. IB4-SAP (Cat. #IT-10) – targets cells expressing alpha-D-galactopyranoside residues #4. mu p75-SAP (Cat. #IT-16) – targets cells expressing mouse p75NTR #5. ME20.4-SAP (Cat. #IT-15) – targets cells expressing multiple mammalian

Top 20 Targeting Tools of 2020 Read More »

A spinal microglia population involved in remitting and relapsing neuropathic pain

Kohno K, Shirasaka R, Yoshihara K, Mikuriya S, Tanaka K, Takanami K, Inoue K, Sakamoto H, Ohkawa Y, Masuda T, Tsuda M (2022) A spinal microglia population involved in remitting and relapsing neuropathic pain. Science 376(6588):86-90. doi: 10.1126/science.abf6805 Objective: To investigate pain recovery mechanisms. Summary: The authors reveal a mechanism for the remission and recurrence

A spinal microglia population involved in remitting and relapsing neuropathic pain Read More »

Upregulation of p75NTR by histone deacetylase inhibitors sensitizes human neuroblastoma cells to targeted immunotoxin-induced apoptosis

Dedoni S, Olianas A, Manconi B, Collu M, Tuveri B, Vincis ME, Olianas MC, Onali P (2022) Upregulation of p75NTR by histone deacetylase inhibitors sensitizes human neuroblastoma cells to targeted immunotoxin-induced apoptosis. Int J Mol Sci 23(7):3849. doi: 10.3390/ijms23073849 PMID: 35409209 Summary: Histone deacetylase (HDAC) inhibitors have been useful chemotherapy agents in the treatment of

Upregulation of p75NTR by histone deacetylase inhibitors sensitizes human neuroblastoma cells to targeted immunotoxin-induced apoptosis Read More »

Search
Shopping Cart
Scroll to Top