Author name: Kristen Hartman

Cover Article: Immunolesioning Hippocampal Inhibitory Interneurons

News Article /

Dr. Robert Sloviter, University of Arizona, contributes this issue’s article from the laboratories of ATS customers. Dr. Sloviter summarizes his research with SSP-saporin, which he and his graduate student Jennifer Martin used to examine the role of inhibitory neurons in maintaining normal network excitability. The mammalian hippocampus is perhaps the most intensely studied brain region […]

Cover Article: Immunolesioning Hippocampal Inhibitory Interneurons Read More »

Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn’s disease.

Kanai T, Watanabe M, Okazawa A, Sato T, Yamazaki M, Okamoto S, Ishii H, Totsuka T, Iiyama R, Okamoto R, Ikeda M, Kurimoto M, Takeda K, Akira S, Hibi T (2001) Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn’s disease. Gastroenterol 121:875-888. doi: 10.1053/gast.2001.28021 Summary: Crohn’s disease is an inflammatory bowel disease that

Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn’s disease. Read More »

Recombinant domains of mouse nidogen-1 and their binding to basement membrane proteins and monoclonal antibodies

Ries A, Göhring W, Fox JW, Timpl R, Sasaki T (2001) Recombinant domains of mouse nidogen-1 and their binding to basement membrane proteins and monoclonal antibodies. Eur J Biochem 268(19):5119-5128. doi: 10.1046/j.0014-2956.2001.02437.x PMID: 11589703 Related Products: Antibody to Nidogen, G1 [JF1 (1F1-F5-A10)] (Cat. #AB-V32), Antibody to Nidogen, G3 [JF2 (1E2-A5-A3)] (Cat. #AB-V33), Antibody to Nidogen,

Recombinant domains of mouse nidogen-1 and their binding to basement membrane proteins and monoclonal antibodies Read More »

Long-term intrathecal catheterization in the rat.

Jasmin L, Ohara PT (2001) Long-term intrathecal catheterization in the rat. J Neurosci Methods 110:81-89. doi: 10.1016/s0165-0270(01)00420-4 Summary: The authors have developed a method that allows repeated administration of drugs with minimal stress to an experimental animal. To test the efficacy of this intrathecal catheter, they injected anti-DBH-SAP (5 µg; Cat. #IT-03,) and investigated the

Long-term intrathecal catheterization in the rat. Read More »

Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat.

Gerashchenko D, Kohls MD, Greco M, Waleh NS, Salin-Pascual R, Kilduff TS, Lappi DA, Shiromani PJ (2001) Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. J Neurosci 21(18):7273-7283. doi: 10.1523/JNEUROSCI.21-18-07273.2001 PMID: 11549737 Summary: Orexin (also knows as hypocretin) peptides are produced exclusively by neurons in the lateral hypothalamus, however non-specific

Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. Read More »

Effects of hypocretin-saporin injections into the medial septum on sleep and hippocampal theta.

Gerashchenko D, Salin-Pascual R, Shiromani PJ (2001) Effects of hypocretin-saporin injections into the medial septum on sleep and hippocampal theta. Brain Res 913:106-115. doi: 10.1016/s0006-8993(01)02792-5 Summary: Hypocretin, also known as orexin, neurons are located only in the lateral hypothalamus. Recently, the loss of these neurons was shown to be associated with narcolepsy. The authors used

Effects of hypocretin-saporin injections into the medial septum on sleep and hippocampal theta. Read More »

Extensive immunolesions of basal forebrain cholinergic system impair offspring recognition in sheep.

Ferreira G, Meurisse M, Gervais R, Ravel N, Levy F (2001) Extensive immunolesions of basal forebrain cholinergic system impair offspring recognition in sheep. Neuroscience 106(1):103-116. doi: 10.1016/s0306-4522(01)00265-2 Summary: Through the use of 192-Saporin (Cat. #IT-01) the association of basal forebrain cholinergic neurons to learning instrumental tasks has been well established in the rat. The authors

Extensive immunolesions of basal forebrain cholinergic system impair offspring recognition in sheep. Read More »

Hippocampal sympathetic ingrowth occurs following 192-IgG-saporin administration.

Harrell LE, Parsons D, Kolasa K (2001) Hippocampal sympathetic ingrowth occurs following 192-IgG-saporin administration. Brain Res 911:158-162. doi: 10.1016/s0006-8993(01)02626-9 Summary: Electrolytic lesions of the medial septal region in rats cause peripheral sympathetic fibers from the superior cervical ganglia to grow into the cholinergically-denervated areas of the hippocampus. This lesioning method is non-specific and disrupts several

Hippocampal sympathetic ingrowth occurs following 192-IgG-saporin administration. Read More »

Dissociation between the attentional functions mediated via basal forebrain cholinergic and GABAergic neurons.

Burk JA, Sarter M (2001) Dissociation between the attentional functions mediated via basal forebrain cholinergic and GABAergic neurons. Neuroscience 105(4):899-909. doi: 10.1016/s0306-4522(01)00233-0 Summary: The specificity and efficacy of 192-Saporin (Cat. #IT-01) has allowed the extensive investigation of cortical cholinergic inputs in attentional functions. Little is known about the function of non-cholinergic neurons because of the

Dissociation between the attentional functions mediated via basal forebrain cholinergic and GABAergic neurons. Read More »

Search
Shopping Cart
Scroll to Top