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Extensive immunolesions of basal forebrain cholinergic system impair offspring recognition in sheep.

Ferreira G, Meurisse M, Gervais R, Ravel N, Levy F (2001) Extensive immunolesions of basal forebrain cholinergic system impair offspring recognition in sheep. Neuroscience 106(1):103-116. doi: 10.1016/s0306-4522(01)00265-2

Summary: Through the use of 192-Saporin (Cat. #IT-01) the association of basal forebrain cholinergic neurons to learning instrumental tasks has been well established in the rat. The authors wished to examine whether these neurons were also associated with social learning tasks, such as offspring recognition in sheep. Using ME20.4-SAP (Cat. #IT-15) the basal forebrain cholinergic neurons of sheep were lesioned by intraventricular bilateral injections (150 µg). The results demonstrate that these neurons contribute to visual discrimination learning, and are involved in formation of lamb recognition memory.

Related Products: 192-IgG-SAP (Cat. #IT-01), ME20.4-SAP (Cat. #IT-15)

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