Author name: Kristen Hartman

Antiplexin D1 antibodies relate to small fiber neuropathy and induce neuropathic pain in animals

Fujii T, Lee EJ, Miyachi Y, Yamasaki R, Lim YM, Iinuma K, Sakoda A, Kim KK, Kira JI (2021) Antiplexin D1 antibodies relate to small fiber neuropathy and induce neuropathic pain in animals. Neurol Neuroimmunol Neuroinflamm 8(5):e1028. doi: 10.1212/NXI.0000000000001028 Summary: NeP patient-derived plexin D1-IgG selectively binds to isolectin B4-positive unmyelinated C-fiber type small DRG neurons […]

Antiplexin D1 antibodies relate to small fiber neuropathy and induce neuropathic pain in animals Read More »

The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity

Maejima Y, Yokota S, Shimizu M, Horita S, Kobayashi D, Hazama A, Shimomura K (2021) The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity. Nutr Metab (Lond) 18(1):58. doi: 10.1186/s12986-021-00582-z Summary: Feeding rhythm disruption contributes to the development of obesity. GLP-1

The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity Read More »

Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine

Yuan H, Hu H, Chen R, Mu W, Wang L, Li Y, Chen Y, Ding X, Xi Y, Mao S, Jiang M, Chen J, He Y, Wang L, Dong Y, Tou J, Chen W (2021) Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine. Stem Cells

Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine Read More »

Implication of RAS in postnatal cardiac remodeling, fibrosis and dysfunction induced by fetal undernutrition

Rodríguez-Rodríguez P, Vieira-Rocha MS, Quintana-Villamandos B, Monedero-Cobeta I, Prachaney P, López de Pablo AL, González MDC, Morato M, Diniz C, Arribas SM (2021) Implication of RAS in postnatal cardiac remodeling, fibrosis and dysfunction induced by fetal undernutrition. Pathophysiology 28(2):273-290. doi: 10.3390/pathophysiology28020018 PMID: 35366262 Objective: To assess if alterations in renal artery stenosis (RAS) during lactation

Implication of RAS in postnatal cardiac remodeling, fibrosis and dysfunction induced by fetal undernutrition Read More »

A5 noradrenergic neurons and breathing control in neonate rats

Taxini CL, Marques DA, Bícego KC, Gargaglioni LH (2021) A5 noradrenergic neurons and breathing control in neonate rats. Pflugers Arch 473(6):859-872. doi: 10.1007/s00424-021-02550-1 Summary: In this study, the authors investigated the participation of A5 noradrenergic neurons in neonates (P7-8 and P14-15) in the control of ventilation during hypoxia and hypercapnia. data suggest that noradrenergic neurons

A5 noradrenergic neurons and breathing control in neonate rats Read More »

Identification and therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumorswith DS-6157a, a first-in-class antibody-drug conjugate

Iida K, Abdelhamid Ahmed AH, Nagatsuma AK, Shibutani T, Yasuda S, Kitamura M, Hattori C, Abe M, Hasegawa J, Iguchi T, Karibe T, Nakada T, Inaki K, Kamei R, Abe Y, Nomura T, Andersen JL, Santagata S, Hemming ML, George S, Doi T, Ochiai A, Demetri GD, Agatsuma T (2021) Identification and therapeutic targeting of

Identification and therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumorswith DS-6157a, a first-in-class antibody-drug conjugate Read More »

Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data

Nazmuddin M, Philippens IHCHM, van Laar T (2021) Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data. Sci Rep 11(1):11751. doi: 10.1038/s41598-021-91391-0 Objective: Review the design of stimulation experiments on the nucleus basalis of Meynert (NBM) and its effects on behavioral and neurophysiological aspects. Summary: Deep brain stimulation

Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data Read More »

Utilization of pectoralis minor accessory inspiratory muscles in a rodent model of respiratory motor neuron loss

Borkowski L, Nichols N (2021) Utilization of pectoralis minor accessory inspiratory muscles in a rodent model of respiratory motor neuron loss. FASEB J 35(S1) Experimental Biology 2021 Meeting Abstracts. doi: 10.1096/fasebj.2021.35.S1.01843 PMID: 0 Objective: To develop a model of selective respiratory motor neuron death to study how breathing is impacted and advance targeted therapeutic interventions.

Utilization of pectoralis minor accessory inspiratory muscles in a rodent model of respiratory motor neuron loss Read More »

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