Author name: Kristen Hartman

Depletion of rostral ventrolateral medullary catecholaminergic neurons impairs the hypoxic ventilatory response in conscious rats.

Malheiros-Lima M, Takakura A, Moreira T (2017) Depletion of rostral ventrolateral medullary catecholaminergic neurons impairs the hypoxic ventilatory response in conscious rats. Neuroscience 351:1-14.. doi: 10.1016/j.neuroscience.2017.03.031 Related Products: Anti-DBH-SAP (Cat. #IT-03)

Depletion of rostral ventrolateral medullary catecholaminergic neurons impairs the hypoxic ventilatory response in conscious rats. Read More »

The identification of ᴅ-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis.

Kobayashi K, Maezawa T, Tanaka H, Onuki H, Horiguchi Y, Hirota H, Ishida T, Horiike K, Agata Y, Aoki M, Hoshi M, Matsumoto M (2017) The identification of ᴅ-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis. Sci Rep 7:45175. doi: 10.1038/srep45175 PMID: 28338057 Usage: IHC 1:50

The identification of ᴅ-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis. Read More »

The rostromedial tegmental nucleus and alcohol addiction

Ye J-H, Fu R, He W (2017) The rostromedial tegmental nucleus and alcohol addiction. Oncotarget 8:18624-18625.. doi: 10.18632/oncotarget.15822 Summary: The authors discuss their work with Dermorphin-SAP (Cat. #IT-12) and their demonstration that damage of RMTg MOR-expressing GABAergic neurons by Dermorphin-SAP increased the intake and preference for alcohol, boosted the expression and slowed down the extinction

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Neurite outgrowth in cultured mouse pelvic ganglia – Effects of neurotrophins and bladder tissue

Ekman M, Zhu B, Swärd K, Uvelius B (2017) Neurite outgrowth in cultured mouse pelvic ganglia – Effects of neurotrophins and bladder tissue. Auton Neurosci 205:41-49. doi: 10.1016/j.autneu.2017.03.004 PMID: 28347639 Objective: To characterize the effects of the neurotrophins nerve growth factor (NGF), brain derived neurotrophic factor (BDNF) and neurotrophin 3 (NT-3) on the sprouting rate

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PARK2 depletion connects energy and oxidative stress to PI3K/Akt activation via PTEN S-Nitrosylation

Gupta A, Anjomani-Virmouni S, Koundouros N, Dimitriadi M, Choo-Wing R, Valle A, Zheng Y, Chiu YH, Agnihotri S, Zadeh G, Asara JM, Anastasiou D, Arends MJ, Cantley LC, Poulogiannis G (2017) PARK2 depletion connects energy and oxidative stress to PI3K/Akt activation via PTEN S-Nitrosylation. Mol Cell 65(6):999-101.e7. doi: 10.1016/j.molcel.2017.02.019 PMID: 28306514 Objective: To investigate the

PARK2 depletion connects energy and oxidative stress to PI3K/Akt activation via PTEN S-Nitrosylation Read More »

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

Gholamin S, Mitra SS, Feroze AH, Liu J, Kahn SA, Zhang M, Esparza R, Richard C, Ramaswamy V, Remke M, Volkmer AK, Willingham S, Ponnuswami A, McCarty A, Lovelace P, Storm TA, Schubert S, Hutter G, Narayanan C, Chu P, Raabe EH, Harsh G 4th, Taylor MD, Monje M, Cho YJ, Majeti R, Volkmer JP,

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors Read More »

Lipid Link to Neuro-Degenerative Disease

Martínez-Gardeazabal J, González de San Román E, Moreno-Rodríguez M, Llorente-Ovejero A, Manuel I, Rodríguez-Puertas R. (2017) Lipid Mapping of the Rat Brain for Models of Disease. Biochim Biophys Acta  PMID:28235468 The major components of plasma membranes are lipids. These molecules have a wide range of functions including cellular structure, metabolism and signaling molecules.  Regarding this

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Molecular and neural basis of contagious itch behavior in mice

Yu Y-Q, Barry DM, Hao Y, Liu X-T, Chen Z-F (2017) Molecular and neural basis of contagious itch behavior in mice. Science 355:1072. doi: 10.1126/science.aak9748 Summary: The authors selectively ablated the SCN gastrin-releasing peptide receptor (GRPR) neurons using Bombesin-SAP (Cat. #IT-40), a peptide-conjugated toxin that kills GRPR neurons in the spinal cord. After bilateral injection

Molecular and neural basis of contagious itch behavior in mice Read More »

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