Author name: Kristen Hartman

Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization

Wang D, Wang A, Wu F, Qiu X, Li Y, Chu J, Huang WC, Xu K, Gong X, Li S (2017) Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. Sci Rep 7:40295. doi: 10.1038/srep40295 PMID: 28071739 Objective: To show that Sox10+ adult stem cells contribute to both encapsulation and microvessel formation. Summary: This […]

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Accelerating Your Research

As we start a new year, we at Advanced Targeting Systems are more dedicated than ever to providing our customers with the innovative, cutting-edge tools that will accelerate and optimize research. Scientists around the world have published exciting new data to advance our knowledge of how specific cell types affect behavior and disease. With each new discovery, possibilities

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Murine neural crest stem cells and embryonic stem cell-derived neuron precursors survive and differentiate after transplantation in a model of dorsal root avulsion

Konig N, Trolle C, Kapuralin K, Adameyko I, Mitrecic D, Aldskogius H, Shortland PJ, Kozlova EN (2017) Murine neural crest stem cells and embryonic stem cell-derived neuron precursors survive and differentiate after transplantation in a model of dorsal root avulsion. J Tissue Eng Regen Med 11(1):129-137. doi: 10.1002/term.1893 PMID: 24753366 Objective: To compare survival and

Murine neural crest stem cells and embryonic stem cell-derived neuron precursors survive and differentiate after transplantation in a model of dorsal root avulsion Read More »

Featured Article: The locus coeruleus: a potential link between cerebrovascular and neuronal pathology in Alzheimer’s disease.

Kelly SC, Nelson PT, Counts SE (2017) Featured Article: The locus coeruleus: a potential link between cerebrovascular and neuronal pathology in Alzheimer’s disease. Targeting Trends 18 Related Products: Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18) Read the featured article in Targeting Trends. See Also: Kelly SC et al. The locus coeruleus: a potential link between

Featured Article: The locus coeruleus: a potential link between cerebrovascular and neuronal pathology in Alzheimer’s disease. Read More »

Electrospun polycaprolactone/chitosan scaffolds for nerve tissue engineering: physicochemical characterization and Schwann cell biocompatibility

Bolaina-Lorenzo E, Martínez-Ramos C, Monleón-Pradas M, Herrera-Kao W, Cauich-Rodríguez JV, Cervantes-Uc JM (2016) Electrospun polycaprolactone/chitosan scaffolds for nerve tissue engineering: physicochemical characterization and Schwann cell biocompatibility. Biomed Mater 12(1):015008. doi: 10.1088/1748-605x/12/1/015008 PMID: 27934786 Objective: To study the effect of scaffold compositions on its physicochemical and biological properties. Summary: Immunochemistry analysis with p75 analysis confirmed that

Electrospun polycaprolactone/chitosan scaffolds for nerve tissue engineering: physicochemical characterization and Schwann cell biocompatibility Read More »

Cholinergic basal forebrain lesion decreases neurotrophin signaling without affecting tau hyperphosphorylation in genetically susceptible mice.

Turnbull M, Coulson E (2017) Cholinergic basal forebrain lesion decreases neurotrophin signaling without affecting tau hyperphosphorylation in genetically susceptible mice. J Alzheimers Dis 55:1141-1154.. doi: 10.3233/JAD-160805 Summary: Alzheimer’s disease(AD) is a progressive, irreversible neurodegenerative disease that destroys memory and cognitive function. Aggregates of hyperphosphorylated tau protein are a prominent feature in the brain of patients

Cholinergic basal forebrain lesion decreases neurotrophin signaling without affecting tau hyperphosphorylation in genetically susceptible mice. Read More »

Transcriptomic analysis of mouse cochlear supporting cell maturation reveals large-scale changes in notch responsiveness prior to the onset of hearing.

Maass J, Gu R, Cai T, Wan Y, Cantellano S, Asprer J, Zhang H, Jen H, Edlund R, Liu Z, Groves A (2016) Transcriptomic analysis of mouse cochlear supporting cell maturation reveals large-scale changes in notch responsiveness prior to the onset of hearing. PLoS One 11:e0167286. doi: 10.1371/journal.pone.0167286 PMID: 27918591 Summary: The ability of neonatal

Transcriptomic analysis of mouse cochlear supporting cell maturation reveals large-scale changes in notch responsiveness prior to the onset of hearing. Read More »

Identification of novel macropinocytosing human antibodies by phage display and high-content analysis.

Ha K, Bidlingmaier S, Su Y, Lee N, Liu B (2017) Identification of novel macropinocytosing human antibodies by phage display and high-content analysis. Methods Enzymol 585:91-110. doi: 10.1016/bs.mie.2016.10.004 Objective: To describe a method for identifying antibodies that internalize via macropinocytosis by screening phage-displayed single-chain antibody selection outputs with an automated fluorescent microscopy-based high-content analysis platform.

Identification of novel macropinocytosing human antibodies by phage display and high-content analysis. Read More »

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