17q1

Targeting Trends 2017 Newsletter

The locus coeruleus: a potential link between cerebrovascular and neuronal pathology in Alzheimer’s disease. / by S C Kelly, P T Nelson, S E Counts / featuring Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18) From the President: Accelerating Your Research Fab-pHAST: The newest targeting tool Recent Scientific References and Publications Talking about Targeting: Neurotransmitter Antibodies

Targeting Topics 17q1

Photoentrainment and Pupillary Light Reflex Are Mediated By Distinct Populations of Iprgcs. Chen SK, Badea TC, Hattar S. Nature 476(7358):92-95, 2011. PMID: 21765429 Intinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment Melanopsin and regulate a wide array of light dependent physiological processes. Genetic ablation of ipRGCs eliminates circadian photoentrainment and severely disrupts the pupillary …

Targeting Topics 17q1 Read More »

Targeting Talk: Neurotransmitter Antibodies

Advanced Targeting Systems offers a full line of antibodies to neurotransmitters; everything from serotonin and L-DOPA, to noradrenaline and dopamine. These antibodies are an excellent choice for immunohistochemistry applications as they are ideally primed for use in tissues that have been perfused with a mixture of paraformaldehyde and gluteraldehyde. Some frequently asked questions: Q:  Could you …

Targeting Talk: Neurotransmitter Antibodies Read More »

Fab-pHAST: The newest targeting tool

Contributed by Patrick Shramm, Product Manager for Fab-pHast We are pleased to announce a new set of tools to rapidly screen antibodies, Fab-pHast conjugates. The ATS pHAST product line provides the FASTEST results in quantitative testing of your antibody’s specific-binding and internalization. Fab-pHast contains a pH-dependent fluorescent reporter that increases intensity in acidic surroundings, such …

Fab-pHAST: The newest targeting tool Read More »

Cover Article: The locus coeruleus: a potential link between cerebrovascular and neuronal pathology in Alzheimer’s disease.

Contributed by S C Kelly, P T Nelson, S E Counts Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that most commonly affects individuals over the age of 65. While of unknown etiology, AD is characterized by a steady decline in cognitive functions including memory, attention, executive functions, and language. There is currently no disease-modifying therapy …

Cover Article: The locus coeruleus: a potential link between cerebrovascular and neuronal pathology in Alzheimer’s disease. Read More »

Accelerating Your Research

As we start a new year, we at Advanced Targeting Systems are more dedicated than ever to providing our customers with the innovative, cutting-edge tools that will accelerate and optimize research. Scientists around the world have published exciting new data to advance our knowledge of how specific cell types affect behavior and disease. With each new discovery, possibilities …

Accelerating Your Research Read More »