16q2

Targeting Trends 2016 Newsletter

Read the 2016 newsletters Recent Scientific References 2016, issue 1: Striatal patch compartment lesions reduce cocaine-induced repetitive behaviors / by KA Horner and collaborators R Murray and MC Logan Mercer / featuring Dermorphin-SAP (Cat. #IT-12) From the President: New Beginnings Targeting Talk: Safety of the Toxin Featured Products: Custom Conjugates 2016, issue 2: Cerebral cholinergic …

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Kermit Judges from on High

For years ATS customers have been Gangsta and Kermit fans, and now it is time to show your love by adding a caption to Kermit’s picture!  Each quarter we will post a picture of Kermit up to his usual hijinks and ask our readership to offer their most creative captions.  Be clever and creative as Kermit …

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Toolbox: vGAT Products

ATS is pleased to present a new product line specific for the vesicular GABA transporter (vGAT) protein. vGAT mediates both the accumulaXon of GABA into synaptic vesicles and its release from nerve terminals. vGAT is expressed in nerve endings of GABAergic neurons throughout the CNS. The GABAergic system is crucial to the development and functional …

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From the President: A Sigh is (Not) Just a Sigh . . .

The fundamental things apply. “The Peptidergic Control Circuit for Sighing,” recently published in the prestigious journal Nature, has made us rethink our fundamental belief that sighs are only “long, deep breaths expressing sadness, relief or exhaustion.” Often prompting someone to say, “What’s wrong?” As it turns out, sighs “also occur spontaneously every few minutes to …

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Cover Article: Cerebral cholinergic lesion reduces operant responses to unpleasant thermal stimuli

by Ronald G. Wiley, M.D., Ph.D., Departments of Neurology and Pharmacology, Vanderbilt University, Nashville, TN  and C. J. Vierck, Department of Neuroscience, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL, USA Degeneration of the cholinergic basal forebrain (CBF: medial septum, diagonal band of Broca, nucleus basalis of Meynert/substantia innominata) is a prominent …

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