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Targeting Trends 2015 Newsletter

Read the 2015 Newsletters Recent Scientific References 2015, issue 1: Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in Parkinson’s Disease / by Aaron Kucinski / featuring 192-IgG-SAP (Cat. #IT-01), Anti-ChAT-SAP (Cat. #IT-42) Society for Neuroscience Poster of the Year Award Veterinary Development of Substance P-Saporin (SP-SAP) Targeting Talk: Protocols …

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Targeting Tools: Product Managers Highlight Their Products

While recombinant IB4-SAP (rIB4-SAP, Cat. #IT-10) has traditionally been used to eliminate cell populations that display alpha-D-galactose on the cell membrane, such as non-peptidergic c-fiber nociceptor neurons, it has also been found to be a very effective way to create stable transfected cell lines without the use of drug resistance genes. A recent publication by …

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Targeting Tools: Beta Products. Great Opportunity for Discovery at a Very Low Price.

Saporin conjugates specifically eliminate cells identified by an extracellular marker. Each week we release new products for beta testing, so check out the website frequently. There are two conjugate configurations for Beta products. The first is a direct conjugate of the targeting agent to saporin; the second is a bonded toxin between the targeting agent …

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Cover Article: SP-SAP Human Clinical Trial for Cancer Pain – An Anesthesiologist’s Point of View

by Carl Noe, M.D., Anesthesiology & Pain Management, UT Southwestern Medical Center, Dallas, TX; and Eugene McDermott Center for Pain Management, Dallas, Texas Dr. Noe is the Principal Investigator in the ongoing trial of SP-SAP Intrathecal SP-SAP (Substance P attached to the ribosome-inactivating protein, saporin) has been studied in a Phase 1 clinical trial of …

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