Saporin conjugates specifically eliminate cells identified by an extracellular marker. Each week we release new products for beta testing, so check out the website frequently. There are two conjugate configurations for Beta products. The first is a direct conjugate of the targeting agent to saporin; the second is a bonded toxin between the targeting agent and the secondary conjugate Streptavidin-ZAP (Cat. #IT-27; saporin attached to streptavidin). Each of the Beta products has saporin activity confirmed plus Peptide sequences and/or Antibody binding specificity published/confirmed.
Nociceptin-SAP (Cat. #BETA-001) bonded toxin • targeting agent: nociceptin
Octreotide-SAP (Cat. #BETA-002) bonded toxin • targeting agent: octreotide peptide
Azido-ZAP (Cat. #BETA-003) direct conjugate • targeting agent: terminal azide group
Anti-CB1-SAP (Cat. #BETA-005) bonded toxin • targeting agent: Ab to hum/rat cannabinoid receptor 1
Deltorphin-SAP (Cat. #BETA-006) direct conjugate • targeting agent: deltorphin
Anti-OX1r-SAP (Cat. #BETA-007) bonded toxin • targeting agent: antibody to mouse, rat, guinea pig orexin 1 receptor
Anti-OX2r-SAP (Cat. #BETA-008) bonded toxin • targeting agent: antibody to rat orexin 2 receptor
Exenatide-4-SAP (GLP-1-SAP; Cat. #BETA-009) bonded toxin • targeting agent: exendin-4 peptide, a glucagon-like peptide-1 agonist
Chlorotoxin-SAP (Cat. #BETA-010) bonded toxin • targeting agent: chlorotoxin
CGRP-SAP (Cat. #BETA-011) bonded toxin • targeting agent: a-CGRP
Methotrexate-SAP (Cat. #BETA-012) direct conjugate • targeting agent: Methotrexate
MOA-SAP (Cat. # BETA-013) bonded toxin • targeting agent: blood group B lectin from Marasmius Oreades
Anti-PD-L1-SAP (Cat. #BETA-014) bonded toxin • targeting agent: antibody to human PD-L1
Anti-CD105-SAP (Cat. #BETA-015) bonded toxin • targeting agent: antibody to human CD105
Anti-CD38-SAP (Cat. #BETA-016) bonded toxin • targeting agent: antibody to mouse CD38
Anti-Cripto-SAP (Cat. #BETA-017) bonded toxin • targeting agent: antibody to mouse/human Cripto-1
Anti-CXCR4-SAP (Cat. #BETA-018) bonded toxin • targeting agent: antibody to human CXCR4
Anti-MC4R-SAP (Cat. #BETA-020) bonded toxin • targeting agent: antibody to human MC4R
ACTH-SAP (Cat. #BETA-021) bonded toxin • targeting agent: ACTH peptide
aMSH-SAP (Cat. #BETA-022) bonded toxin • targeting agent: aMSH peptide
Vasopressin-SAP (Cat. #BETA-023) bonded toxin • targeting agent: vasopressin peptide
Anti-CD15-SAP (Cat. #BETA-024) bonded toxin • targeting agent: antibody to CD15
Anti-CD24-SAP (Cat. #BETA-025) bonded toxin • targeting agent: antibody to human CD24
VIP-SAP (Cat. #BETA-027) bonded toxin • targeting agent: Vasoactive intestinal peptide
GnRH-SAP (Cat.#BETA-028) bonded toxin • targeting agent: GnRH peptide