07q4

Targeting Trends Newsletter 07q4

Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page. Newsletter Highlights Summer Fun (page 2) Flow Cytometry Services (page 2) Teaser Winners (page 5) FGF-SAP, Anti-AChR, and SP-CTA (page 7) Page 1 Page 5 Page 2 …

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Targeting Topics 07q4

Cortical cholinergic deficiency enhances amphetamine-induced dopamine release in the accumbens but not in the striatum Mattsson A, Olson L, Svensson TH, Schilstrom B Exp Neurol 208(1):73-79, 2007. Previous data have implicated cholinergic dysfunction in the pathogenesis of schizophrenia. Here the authors investigated whether increased amphetamine-induced release of dopamine was a response to cortical cholinergic denervation. …

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Cover Article: Inducing Central Sensitization with a Substance P/ Cholera Toxin Conjugate

Contributed by Robert M. Caudle, Ph.D.University of Florida College of Dentistry, Gainesville, FL 32610 A substantial amount of work with Advanced Targeting Systems’ substance P/saporin conjugate (SP-SAP, Cat. #IT-07) has demonstrated that neurokinin-1 (NK1) receptor-expressing neurons in the spinal cord and brain stem are necessary for the full expression of central sensitization following a peripheral …

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