07q4

Targeting Tools: Anti-AChR

Species Reactivity: Human, Rat, Mouse, Rabbit Anti-AChR (Cat. #AB-N36) binds with high affinity to the AChR subtype with 59 kDa ACh-binding subunits, but with considerably lower affinity to the AChR subtype with 75 kDa subunits. Anti-AChR binds to the main immunogenic region on α1 subunits of muscle-type AChRs. Reference 1. Schoepfer R, Halvorsen SW, Conroy …

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Targeting Trends 2007 Newsletter

Read the 2007 Newsletters and recent scientific references 2007, issue 1: Cholinergic Immunolesioning Produced Tangle-like Inclusions in TgCRND8 Brain / by Chauhan N / featuring mu p75-SAP (Cat. #IT-16) SFN Poster of the Year Targeting Talk: Targeted Toxin Controls Targeting Tools Anti-Pseudomonas aeurginosa (Cat. #AB-T057) Anti-Conjugated Glutathione (Cat. #AB-T01) Anti-Conjugated Acetylcholine (Cat. #AB-T02) Anti-Conjugated Dopamine (Cat. #AB-T11) …

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Cover Article: Inducing Central Sensitization with a Substance P/ Cholera Toxin Conjugate

Contributed by Robert M. Caudle, Ph.D.University of Florida College of Dentistry, Gainesville, FL 32610 A substantial amount of work with Advanced Targeting Systems’ substance P/saporin conjugate (SP-SAP, Cat. #IT-07) has demonstrated that neurokinin-1 (NK1) receptor-expressing neurons in the spinal cord and brain stem are necessary for the full expression of central sensitization following a peripheral …

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