Featured Article

Chen ZF, Sun YG, Zhao ZQ, Meng XL, Yin J, Liu XY (2009) Featured Article: Ablation of GRPR+ neurons in the spinal cord by bombesin-saporin knocks out itch sensation in mice without affecting pain circuit. Targeting Trends 10(4)

Related Products: Bombesin-SAP (Cat. #IT-40), Blank-SAP (Cat. #IT-21)

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• Sun YG et al. Cellular basis of itch sensation. Science 325:1531-1534, 2009.

Montero M, Gonzalez B, Zimmer J (2009) Featured Article: Depletion of microglia by Mac-1-SAP in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. Targeting Trends 10(3)

Related Products: Mac-1-SAP mouse/human (Cat. #IT-06)

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• Montero M et al. Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. Brain Res 1291:140-152, 2009.

Khan AM, Rapp KL, Ponzio TA, Sanchez-Watts G, Watts AG (2009) Featured Article: Deletion of catecholaminergic neurons by anti-DBH-saporin disrupts hypothalamic MAP kinase and CREB activation. Targeting Trends 10(2)

Related Products: Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18)

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• Khan AM et al. Stimulus-, circuit- and intracellular-level determinants of MAP kinase and CREB activation in parvicellular hypothalamic paraventricular neurons. Neuroscience 2008 Abstracts 865.23/MM24, 2008. Society for Neuroscience, Washington, DC

Hess PR, Buntzman AS, Murray SL, Young EF, Frelinger JA (2009) Featured Article: Selective deletion of CD8+ T cells by saporin-coupled MHC class I tetramers. Targeting Trends 10(1)

Related Products: Streptavidin-ZAP (Cat. #IT-27), Saporin Goat Polyclonal, affinity-purified FITC-labeled (Cat. #AB-15APFL)

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• Hess PR et al. Selective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin. Blood 109:3300-3307, 2007.

Likhtik E (2008) Featured Article: Selective lesions of amygdala intercalated neurons using the Dermorphin-SAP immunotoxin reveal their role in conditioned fear. Targeting Trends 9(4)

Related Products: Dermorphin-SAP / MOR-SAP (Cat. #IT-12), Blank-SAP (Cat. #IT-21)

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• Likhtik E et al. Amygdala intercalated neurons are required for expression of fear extinction. Nature 454(7204):642-645, 2008.

Radley JJ (2008) Featured Article: Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress. Targeting Trends 9(3)

Related Products: Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18)

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• Radley JJ et al. Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamo-pituitary-adrenal responses to acute emotional stress. J Neurosci 28:5806-5816, 2008.

Moreau PH, Cosquer B, Jeltsch H, Cassel JC, Mathis C (2008) Featured Article: Selective lesion of basal forebrain cholinergic neurons in mice with the mu p75-saporin immunotoxin: Neuroanatomy and behavior. Targeting Trends 9(2)

Related Products: 192-IgG-SAP (Cat. #IT-01), mu p75-SAP (Cat. #IT-16)

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• Moreau PH et al. Neuroanatomical and behavioral effects of a novel version of the cholinergic immunotoxin mu p75-saporin in mice. Hippocampus 18(6):610-622, 2008.

Pang KCH, Jiao X, Servatius RJ (2008) Featured Article: Role of medial septal GABAergic neurons in learning and extinction: Effects of the novel GABA immunotoxin GAT1-SAP. Targeting Trends 9(1)

Related Products: GAT1-SAP (Cat. #IT-32)

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Caudle RM (2007) Featured Article: Inducing central sensitization with a substance P/ cholera toxin conjugate. Targeting Trends 8(4)

Related Products: SP-SAP (Cat. #IT-07), SP-CTA (Cat. #IT-39)

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• Caudle RM Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin. BMC Neuroscience 8:30, 2007.

Potts JT (2007) Featured Article: Nucleus tractus solitarii injections of substance P-conjugated saporin selectively disrupts baroflex-dependent pathways. Targeting Trends 8(2)

Related Products: SP-SAP (Cat. #IT-07)

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• Potts JT et al. Targeted deletion of neurokinin-1 receptor expressing nucleus tractus solitarii neurons precludes somatosensory depression of arterial baroreceptor-heart rate reflex. Neuroscience 145(3):1168-1181, 2007.