References

Wang F, Jing P, Zhan P, Zhang H (2020) Thyroid hormone in the pathogenesis of congenital intestinal dysganglionosis. Pediatr Dev Pathol 23(4):285-295. doi: 10.1177/1093526620908984 PMID: 32212960

Objective: To investigate the role of thyroid hormone (TH) in the pathogenesis of intestinal dysganglionosis (ID).

Summary: 6-propyl-2-thiouracil (PTU) inhibited TH production, reduced the number of enteric neurons, impaired intestinal motility, and impeded ENCC mitosis in zebrafish, suggesting a possible role of CH in the pathogenesis of ID.

Usage: Immunostaining (1:60); AB-N01AP: NGFr (mu p75) Rabbit Polyclonal

Related Products: NGFr (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP)

Ruggiero FM, Rodríguez-Walker M, Daniotti JL (2020) Exploiting the internalization feature of an antibody against the glycosphingolipid SSEA-4 to deliver immunotoxins in breast cancer cells. Immunol Cell Biol 98(3):187-202. doi: 10.1111/imcb.12314 PMID: 31916611

Qian L, Kasas L, Milne MR, Rawashdeh O, Marks N, Sharma A, Bellingham MC, Coulson EJ (2020) Cholinergic basal forebrain degeneration due to obstructive sleep apnoea increases Alzheimer’s pathology in mice. bioRxiv 2020.03.12.989848. doi: 10.1101/2020.03.12.989848

Usage: bilateral injections of urotensin II-saporin (UII-SAP; 0.07 μg/μL per site – unless stated otherwise; generous gift from Advanced Targeting Systems)

Related Products: Custom Conjugates, Blank-SAP (Cat. #IT-21)

Qin J, Wang M, Zhao T, Xiao X, Li X, Yang J, Yi L, Goffinet AM, Qu Y, Zhou L (2020) Early forebrain neurons and scaffold fibers in human embryos. Cerebral Cortex 30(3):913–928. doi: 10.1093/cercor/bhz136 PMID: 31298263

Objective: To study neural progenitor proliferation, neuronal migration, areal organization, and pioneer axon wiring are critical events during early forebrain development.

Summary: Axons from pioneer neurons in prethalamus, ventral telencephalon, and cortical preplate cross the diencephalon–telencephalon junction and the pallial–subpallial boundary, forming scaffolds that could guide thalamic and cortical axons at later stages.

Usage: Immunofluorescence (1:600); AB-N01AP: NGFr (mu p75) Rabbit Polyclonal, affinity-purified

Related Products: NGFr (mu p75) Rabbit Polyclonal, affinity-purified (Cat. #AB-N01AP)

Barry DM, Liu XT, Liu B, Liu XY, Gao F, Zeng X, Liu J, Yang Q, Wilhelm S, Yin J, Tao A, Chen ZF (2020) Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors. Nat Commun 11(1):1397. doi: 10.1038/s41467-020-15230-y

Objective: To determine the role of GRP in sensory neurons.

Summary: GRP is a neuropeptide in sensory neurons for nonhistaminergic itch, and GRP sensory neurons are dedicated to itch transmission.

Usage: Bombesin-SAP (200 ng/5 μL, i.t.) was injected 2 weeks prior to optical stimulation.

Related Products: Bombesin-SAP (Cat. #IT-40)

Bernabe CS, Caliman IF, Truitt WA, Molosh AI, Lowry CA, Hay-Schmidt A, Shekhar A, Johnson PL (2020) Using loss- and gain-of-function approaches to target amygdala-projecting serotonergic neurons in the dorsal raphe nucleus that enhance anxiety-related and conditioned fear behaviors. J Psychopharmacol 34(4):400-411. doi: 10.1177/0269881119900981

Objective: To investigate the role of amygdala-projecting 5-HT neurons in the DR in innate anxiety and conditioned fear behaviors.

Summary: The studies support the hypothesis that amygdala-projecting 5-HT neurons in the DR represent an anxiety and fear-on network.

Usage: Each rat received two bilateral microinjections per site (100 nL each, 1 μM in artificial cerebrospinal fluid) of either Anti-SERT-SAP or the control Mouse IgG-SAP.

Related Products: Anti-SERT-SAP (Cat. #IT-23), Mouse IgG-SAP (Cat. #IT-18)

Li X, Yu M, Yang C (2020) YY1-mediated overexpression of long noncoding RNA MCM3AP-AS1 accelerates angiogenesis and progression in lung cancer by targeting miR-340-5p/KPNA4 axis. J Cell Biochem 121(3):2258-2267. doi: 10.1002/jcb.29448 PMID: 31693222

Usage: western (1:1000)

Related Products: Fibroblast Growth Factor Rabbit Polyclonal, mammalian (Cat. #AB-07)

Serre NBC, Sarthou M, Gigarel O, Figuet S, Corso M, Choulet J, Rofidal V, Alban C, Santoni V, Bourguignon J, Verbruggen N, Ravanel S (2020) Protein lysine methylation contributes to modulating the response of sensitive and tolerant Arabidopsis species to cadmium stress. Plant Cell Environ 43(3):760-774. doi: 10.1111/pce.13692 PMID: 31759334

Usage: Western blot

Related Products: Tri-methyl Lysine Rabbit Polyclonal (Cat. #AB-265)

Wu X, Cao Z, Chen H, Ou Q, Huang X, Wang Y (2020) Downregulation of Linc-RNA activator of myogenesis lncRNA participates in FGF2-mediated proliferation of human periodontal ligament stem cells. J Periodontol 91(3):422-427. doi: 10.1002/JPER.19-0317 PMID: 31378921

Usage: Western (1:1200)

Related Products: Fibroblast Growth Factor Rabbit Polyclonal, mammalian (Cat. #AB-07)

Cutuli D, Landolfo E, Decandia D, Nobili A, Viscomi MT, La Barbera L, Sacchetti S, De Bartolo P, Curci A, D’Amelio M, Farioli-Vecchioli S, Petrosini L (2020) Neuroprotective role of dietary supplementation with omega-3 fatty acids in the presence of basal forebrain cholinergic neurons degeneration in aged mice. Int J Mol Sci 21(5):1741. doi: 10.3390/ijms21051741 PMID: 32143275

Objective: Examine the neuroprotective effects of omega-3 polyunsaturated fatty acids in an Alzheimer’s model of aged mice.

Summary: Aged mice were fed omega-3 polyunsaturated fatty acids (n-3 PUFA) or a caloric-equivalent source of fat without n-3 PUFA. Afterward, mice were subjected to lesioning of the cholinergic system with mu p-75-SAP (Cat. IT-16) and assessed for dementia-like symptoms. Mice fed with n-3 PUFA performed better on memory retention tasks and had more exploratory behaviors.

Usage: Intracerebroventricular (i.c.v.) injections of mu-p75-saporin (IT-16); total dosage 0.6 μg/mouse.

Related Products: mu p75-SAP (Cat. #IT-16)