ATS is pleased to present a new product line specific for the vesicular GABA transporter (vGAT) protein. vGAT mediates both the accumulation of GABA into synaptic vesicles and its release from nerve terminals. vGAT is expressed in nerve endings of GABAergic neurons throughout the CNS. The GABAergic system is crucial to the development and functional […]
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CHOp75 Cells 192-IgG-SAP is the #1 rat p75-lesioning tool available for research use. Our development of CHOp75 cells grew from the need for a stable, reliable cell line to use for Quality Control of each new lot of 192-IgG-SAP. Now, these cells are available for use in laboratories worldwide. CHOp75 cells are standard CHO (Chinese
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We are proud to announce the release of our newly redesigned website. It has been crafted to reflect content our customers access most often and to provide new visitors an easier way to learn about ATS’s products and services. Immediately you will notice streamlined menus, simple navigation and access to the information you need, any
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In an effort to accelerate offering new targeted toxins to our customers, we launched the Beta Product program early in 2015. Publications and collaborations are an invaluable source of independent data to support the efficacy of our products. To help streamline this process, we’ve created a catalog of new targeted toxins that we’re offering to
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Proteins come in all shapes and sizes and don’t always contain a ready-to-conjugate binding site. ATS scientists are conjugation experts when it comes to crosslinking peptides, antibodies, and other proteins. Whether you are in need of a Saporin conjugate, biotin labeling, fluorochrome labeling, ADC’s, or other toxin conjugates, we can help you design a strategy
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The conjugation specialists at Advanced Targeting Systems are proud to announce a new addition to the catalog: MonoBiotin-ZAP Cat. #BT-ZAP Researchers now have more freedom in selecting conjugation strategies. Users have taken advantage of the ability to use biotinylated targeting agents with Streptavidin-ZAP (Cat. #IT-27) a chemical conjugate between saporin and streptavidin. Streptavidin-ZAP converts biotinylated
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Choline acetyltransferase (ChAT) catalyzes the synthesis of the neurotransmitter acetylcholine (ACh) from choline and acetyl-CoA in cholinergic neurons. ChAT serves as a specific marker for cholinergic neurons in both peripheral and central nervous systems. Evidence shows that ChAT exists in two forms inside cholinergic nerve terminals, a soluble hydrophilic form and the membrane-associated amphiphilic form.[1-2]
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While recombinant IB4-SAP (rIB4-SAP, Cat. #IT-10) has traditionally been used to eliminate cell populations that display alpha-D-galactose on the cell membrane, such as non-peptidergic c-fiber nociceptor neurons, it has also been found to be a very effective way to create stable transfected cell lines without the use of drug resistance genes. A recent publication by
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Saporin conjugates specifically eliminate cells identified by an extracellular marker. Each week we release new products for beta testing, so check out the website frequently. There are two conjugate configurations for Beta products. The first is a direct conjugate of the targeting agent to saporin; the second is a bonded toxin between the targeting agent
Targeting Tools: Beta Products. Great Opportunity for Discovery at a Very Low Price. Read More »
Custom Biotinylation, when the “one-step-kit” doesn’t quite meet your needs. Proteins come in all shapes and sizes and don’t always contain a ready-to-conjugate binding site. This and other variables can cause you to look toward one-step kits, often leaving you with un-purified and un-verified conjugate. Let the experts in the field help provide you with
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