Author name: Kristen Hartman

Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation.

Weiner GA, Shah SH, Angelopoulos CM, Bartakova AB, Pulido RS, Murphy A, Nudleman E, Daneman R, Goldberg JL (2019) Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. Nat Commun 10(1):2477. doi: 10.1038/s41467-019-10219-8 Objective: To determine which neurons are responsible for angiogenesis and blood retinal barrier formation. Summary: Anti-ChAT-SAP reduces SAC (starburst […]

Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. Read More »

Altered expression of renin-angiotensin system receptors throughout colorectal adenoma-adenocarcinoma sequence.

Beitia M, Solano-Iturri JD, Errarte P, Sanz B, Perez I, Etxezarraga MC, Loizate A, Asumendi A, Larrinaga G (2019) Altered expression of renin-angiotensin system receptors throughout colorectal adenoma-adenocarcinoma sequence. Int J Med Sci 16(6):813-821. doi: 10.7150/ijms.32599 PMID: 31337954 Usage: immunohistochemistry (1:100) Related Products: Angiotensin II receptor (AT-2R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N28AP)

Altered expression of renin-angiotensin system receptors throughout colorectal adenoma-adenocarcinoma sequence. Read More »

Cardiac hypertrophy in mice submitted to a swimming protocol: Influence of training volume and intensity on myocardial renin-angiotensin system.

Soares DdS, Pinto GH, Lopes A, Caetano DSL, Nascimento TG, Andrades ME, Clausell N, Rohde LEP, Leitão SAT, Biolo A (2019) Cardiac hypertrophy in mice submitted to a swimming protocol: Influence of training volume and intensity on myocardial renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol 316(6):R776-R782. doi: 10.1152/ajpregu.00205.2018 PMID: 31042418 Objective: To analyze

Cardiac hypertrophy in mice submitted to a swimming protocol: Influence of training volume and intensity on myocardial renin-angiotensin system. Read More »

Receptor dependence of BDNF actions in superficial dorsal horn: relation to central sensitization and actions of macrophage colony stimulating factor 1.

Boakye PA, Rancic V, Whitlock KH, Simmons D, Longo FM, Ballanyi K, Smith PA (2019) Receptor dependence of BDNF actions in superficial dorsal horn: relation to central sensitization and actions of macrophage colony stimulating factor 1. J Neurophysiol 121(6):2308-2322. doi: 10.1152/jn.00839.2018 PMID: 30995156 Objective: To find missing steps in understanding how peripheral injury instigates central

Receptor dependence of BDNF actions in superficial dorsal horn: relation to central sensitization and actions of macrophage colony stimulating factor 1. Read More »

Conditioned aversion and neuroplasticity induced by a superagonist of extrasynaptic gabaa receptors: Correlation with activation of the oval BNST neurons and CRF mechanisms.

de Miguel E, Vekovischeva O, Elsilä LV, Panhelainen A, Kankuri E, Aitta-aho T, Korpi ER (2019) Conditioned aversion and neuroplasticity induced by a superagonist of extrasynaptic gabaa receptors: Correlation with activation of the oval BNST neurons and CRF mechanisms. Front Mol Neurosci 12:130. doi: 10.3389/fnmol.2019.00130 PMID: 31178693 Usage: immunohistochemistry (1:250) Related Products: Corticotropin Releasing Hormone

Conditioned aversion and neuroplasticity induced by a superagonist of extrasynaptic gabaa receptors: Correlation with activation of the oval BNST neurons and CRF mechanisms. Read More »

Contribution of microglial reaction to increased nociceptive responses in high-fat-diet (HFD)-induced obesity in male mice.

Liang YJ, Feng SY, Qi YP, Li K, Jin ZR, Jing HB, Liu LY, Cai J, Xing GG, Fu KY. (2019) Contribution of microglial reaction to increased nociceptive responses in high-fat-diet (HFD)-induced obesity in male mice. Brain Behav Immun 80:777-792. doi: 10.1016/j.bbi.2019.05.026 Related Products: Mac-1-SAP mouse/human (Cat. #IT-06)

Contribution of microglial reaction to increased nociceptive responses in high-fat-diet (HFD)-induced obesity in male mice. Read More »

S38. Dissecting the functional heterogeneity of serotonergic systems that regulate fear and panic.

Bernabe C, Caliman I, de Abreu A, Dustrude E, Molosh A, Shekhar A, Johnson P (2019) S38. Dissecting the functional heterogeneity of serotonergic systems that regulate fear and panic. Biol Psychiatry 85(10):S311. doi: 10.1016/j.biopsych.2019.03.789 Objective: To elucidate the role of these serotonergic networks on learned fear and innate panic responses. Summary: LED excitation or lesioning

S38. Dissecting the functional heterogeneity of serotonergic systems that regulate fear and panic. Read More »

Q1 2019 Scientific Review

Targeting Topics /

IT-01: 192-IgG-SAP     • Co-treatment with rivastigmine and idalopirdine reduces the propensity for falls in a rat model of falls in Parkinson’s disease. LID – 10.1007/s00213-018-5150-y [doi]. Koshy Cherian A et al. (2019). Psychopharmacol (Berl), [Epub ahead of print]  Dose: Basal forebrain cholinergic neurons situated in the nucleus basalis and substantia innominata were targeted with

Q1 2019 Scientific Review Read More »

Inhibition of STAT3 activation mediated by toll-like receptor 4 attenuates angiotensin II-induced renal fibrosis and dysfunction

Xu Z, Zou C, Yu W, Xu S, Huang L, Khan Z, Wang J, Liang G, Wang Y (2019) Inhibition of STAT3 activation mediated by toll-like receptor 4 attenuates angiotensin II-induced renal fibrosis and dysfunction. Br J Pharmacol 176(14):2627-2641. doi: 10.1111/bph.14686 PMID: 30958891 Objective: To investigate the underlying mechanisms of STAT3 activation by angiotensin II

Inhibition of STAT3 activation mediated by toll-like receptor 4 attenuates angiotensin II-induced renal fibrosis and dysfunction Read More »

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn.

Nelson TS, Fu W, Donahue RR, Corder GF, Hökfelt T, Wiley RG, Taylor BK (2019) Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn. Sci Rep 9(1):7248. doi: 10.1038/s41598-019-43493-z PMID: 31076578 Objective: To test the relevance of the NPYY1 spinal population to the development and/or maintenance of acute

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn. Read More »

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