Author name: Kristen Hartman

Hosts and heterologous expression strategies of recombinant toxins for therapeutic purposes

di Leandro L, Colasante M, Pitari G, Ippoliti R (2023) Hosts and heterologous expression strategies of recombinant toxins for therapeutic purposes. Toxins (Basel) 15(12):699. doi: 10.3390/toxins15120699 PMID: 38133203 Objective: Review the recombinant expression of toxins from bacterial, plant, or animal species used as components of immunotoxins. Summary: Commercial production of recombinant proteins for therapeutic purposes […]

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Regulation of ethanol-mediated dopamine elevation by glycine receptors located on cholinergic interneurons in the nucleus accumbens

Loftén A, Adermark L, Ericson M, Söderpalm B (2023) Regulation of ethanol-mediated dopamine elevation by glycine receptors located on cholinergic interneurons in the nucleus accumbens. Addict Biol 28(12):e13349. doi: 10.1111/adb.13349 PMID: 38017639 Objective: The aim of this study was to explore the role of glycine receptors (GlyRs) on cholinergic interneurons (CIN) in sustaining extracellular dopamine

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Function of gastrin-releasing peptide receptors in ocular itch transmission in the mouse trigeminal sensory system

Takanami K, Kuroiwa M, Ishikawa R, Imai Y, Oishi A, Hashino M, Shimoda Y, Sakamoto H, Koide T (2023) Function of gastrin-releasing peptide receptors in ocular itch transmission in the mouse trigeminal sensory system. Front Mol Neurosci 16:1280024. doi: 10.3389/fnmol.2023.1280024 PMID: 38098939 Objective: To investigate the role of gastrin-releasing peptide (GRP) and GRP receptor (GRPR)

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Engineered smart materials for RNA based molecular therapy to treat Glioblastoma

Singh RR, Mondal I, Janjua T, Popat A, Kulshreshtha R (2023) Engineered smart materials for RNA based molecular therapy to treat Glioblastoma. Bioact Mater 33:396-426. doi: 10.1016/j.bioactmat.2023.11.007 PMID: 38059120 Objective: A review of non-coding RNA therapy and its targeted delivery of nucleic acids to treat Glioblastoma, emphasizing smart nano-materials. Summary: Nano-carriers of ncRNA can offer

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The specificity landscape of bacterial ribonuclease P

Chamberlain AR, Huynh L, Huang W, Taylor DJ, Harris ME (2023) The specificity landscape of bacterial ribonuclease P. J Biol Chem 300(1):105498. doi: 10.1016/j.jbc.2023.105498 PMID: 38013087 Objective: Review of the specificity of ribonucleoprotein RNase P in binding different types of RNA. Summary: Ribonucelase P is involved in the RNA metabolism pathways. By studying the rate

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Neuroscience

Targeting Topics /

The Advanced Targeting Systems targeting technology provides neuroscientists with the tools to identify, visualize, and or eliminate specific cell types. Some examples of scientific studies using ATS products include Learning and Memory, Circadian Rhythm, Sleeping and Wakefulness, Parkinson’s Disease, Alzheimer’s Disease, Addiction, Multiple Sclerosis, Pain Mechanisms, Eating and Diet. Learning and Memory Galanin-SAP [IT-34] PACAP-SAP

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Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract

Zlatkovic J, Dalmau Gasull A, Hägg D, Font-Gironès F, Bellman J, Meister B, Palsdottir V, Ruud J, Ohlsson C, Dickson SL, Anesten F, Jansson JO (2023) Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract. J Neuroendocrinol 35(12):e13352. doi: 10.1111/jne.13352 PMID: 37885347

Reduction of body weight by increased loading is associated with activation of norepinephrine neurones in the medial nucleus of the solitary tract Read More »

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