Author name: Kristen Hartman

Proline hydroxylation primes protein kinases for autophosphorylation and activation

Lee SB, Ko A, Oh YT, Shi P, D’Angelo F, Frangaj B, Koller A, Chen EI, Cardozo T, Iavarone A, Lasorella A (2020) Proline hydroxylation primes protein kinases for autophosphorylation and activation. Mol Cell 79(3):376-389.e8. doi: 10.1016/j.molcel.2020.06.021 PMID: 32640193 Objective: To investigate the formation of prolyl-hydroxylated intermediates as a novel mechanism of kinase maturation and […]

Proline hydroxylation primes protein kinases for autophosphorylation and activation Read More »

The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli.

Kucharczyk MW, Chisholm KI, Denk F, Dickenson AH, Bannister K, McMahon SB (2020) The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli. Pain 161(8):1894-1905. doi: 10.1097/j.pain.0000000000001880 PMID: 32701848 Usage: immunohistochemistry (1:400) Related Products: trkA Rabbit Polyclonal (Cat. #AB-N03)

The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli. Read More »

Photosensitizer with illumination enhances in vivo antitumor effect of anti-robo1 immunotoxin on maxillary sinus squamous cell carcinoma

Komatsu N, Komatsu M, Ohashi R, Horii A, Hoshi K, Takato T, Abe T, Hamakubo T (2020) Photosensitizer with illumination enhances in vivo antitumor effect of anti-robo1 immunotoxin on maxillary sinus squamous cell carcinoma. Anticancer Res 40(7):3792-3799. doi: 10.21873/anticanres.14368 PMID: 32620618 Objective: To focus on the axon guidance receptor roundabout guidance receptor 1 (ROBO1) as

Photosensitizer with illumination enhances in vivo antitumor effect of anti-robo1 immunotoxin on maxillary sinus squamous cell carcinoma Read More »

Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.

Knuplez E, Krier-Burris R, Cao Y, Marsche G, O’Sullivan J, Bochner BS (2020) Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls. J Leukoc Biol 108:43-58. doi: 10.1002/jlb.3hi0120-381r Objective: To determine if targeting Siglec-8 with mouse IgG1 antibodies, rather than targeting Siglec-F with rat IgG antibodies, in mice

Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls. Read More »

Vitamin C decreases VEGF expression levels via hypoxia‑inducible factor‑1α dependent and independent pathways in lens epithelial cells.

Zhao L, Wang J, Zhang Y, Wang L, Yu M, Wang F (2020) Vitamin C decreases VEGF expression levels via hypoxia‑inducible factor‑1α dependent and independent pathways in lens epithelial cells. Mol Med Rep 22(1):436-444. doi: 10.3892/mmr.2020.11103 PMID: 32377733 Objective: To investigate the mechanisms underlying the effects of vitamin C on the expression levels of VEGF.

Vitamin C decreases VEGF expression levels via hypoxia‑inducible factor‑1α dependent and independent pathways in lens epithelial cells. Read More »

Activation of the renin-angiotensin system in high fructose-induced metabolic syndrome.

Kim M, Do GY, Kim I (2020) Activation of the renin-angiotensin system in high fructose-induced metabolic syndrome. Korean J Physiol Pharmacol 24(4):319-328. doi: 10.4196/kjpp.2020.24.4.319 PMID: 32587126 Objective: To investigate the hypothesis that high fructose intake induces activation of the renin-angiotensin systems (RAS), resulting in hypertension and metabolic syndrome. Summary: High fructose intake increased serum renin,

Activation of the renin-angiotensin system in high fructose-induced metabolic syndrome. Read More »

Effects of adjuvant-induced arthritis on the ventral prostate of rats treated with angiotensin AT1 receptor blocker

da Rocha ES, Gomes FC, de Oliveira MR, Bruneto RV, Borges RMR, de Carvalho EP, Angeli-Junior EV, Garcia-Filho GF, Doná JPL, de Oliveira Batanero RP, Carlos CP, de Melo-Neto JS (2020) Effects of adjuvant-induced arthritis on the ventral prostate of rats treated with angiotensin AT1 receptor blocker. Life Sci 252:117629. doi: 10.1016/j.lfs.2020.117629 PMID: 32247619 Objective:

Effects of adjuvant-induced arthritis on the ventral prostate of rats treated with angiotensin AT1 receptor blocker Read More »

Integration of peripheral and central systems in control of ingestive and reproductive behavior

Schneider J (2020) Integration of peripheral and central systems in control of ingestive and reproductive behavior. Oxford Research Encyclopedia of Neuroscience . Oxford University Press doi: 10.1093/acrefore/9780190264086.013.23 Summary: Highly glucose-sensitive cells in the ventrolateral medulla send catecholaminergic projections to the PVH. These projections can be selectively destroyed by Anti-DBH-SAP “DSAP” experiments show that catecholaminergic projections

Integration of peripheral and central systems in control of ingestive and reproductive behavior Read More »

Increased expression of connexin 43 in a mouse model of spinal motoneuronal loss

Spitale FM, Vicario N, Rosa MD, Tibullo D, Vecchio M, Gulino R, Parenti R (2020) Increased expression of connexin 43 in a mouse model of spinal motoneuronal loss. Aging (Albany NY) 12(13):12598-12608. doi: 10.18632/aging.103561 PMID: 32579130 Objective: To investigate the role of the main astroglial gap junctions (GJs)-forming connexin, Cx43, in human Amyotrophic lateral sclerosis

Increased expression of connexin 43 in a mouse model of spinal motoneuronal loss Read More »

Search
Shopping Cart
Scroll to Top