Author name: Kristen Hartman

A5 noradrenergic neurons and breathing control in neonate rats

Taxini CL, Marques DA, Bícego KC, Gargaglioni LH (2021) A5 noradrenergic neurons and breathing control in neonate rats. Pflugers Arch 473(6):859-872. doi: 10.1007/s00424-021-02550-1 Summary: In this study, the authors investigated the participation of A5 noradrenergic neurons in neonates (P7-8 and P14-15) in the control of ventilation during hypoxia and hypercapnia. data suggest that noradrenergic neurons […]

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Identification and therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumorswith DS-6157a, a first-in-class antibody-drug conjugate

Iida K, Abdelhamid Ahmed AH, Nagatsuma AK, Shibutani T, Yasuda S, Kitamura M, Hattori C, Abe M, Hasegawa J, Iguchi T, Karibe T, Nakada T, Inaki K, Kamei R, Abe Y, Nomura T, Andersen JL, Santagata S, Hemming ML, George S, Doi T, Ochiai A, Demetri GD, Agatsuma T (2021) Identification and therapeutic targeting of

Identification and therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumorswith DS-6157a, a first-in-class antibody-drug conjugate Read More »

Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine

Yuan H, Hu H, Chen R, Mu W, Wang L, Li Y, Chen Y, Ding X, Xi Y, Mao S, Jiang M, Chen J, He Y, Wang L, Dong Y, Tou J, Chen W (2021) Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine. Stem Cells

Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine Read More »

Implication of RAS in postnatal cardiac remodeling, fibrosis and dysfunction induced by fetal undernutrition

Rodríguez-Rodríguez P, Vieira-Rocha MS, Quintana-Villamandos B, Monedero-Cobeta I, Prachaney P, López de Pablo AL, González MDC, Morato M, Diniz C, Arribas SM (2021) Implication of RAS in postnatal cardiac remodeling, fibrosis and dysfunction induced by fetal undernutrition. Pathophysiology 28(2):273-290. doi: 10.3390/pathophysiology28020018 PMID: 35366262 Objective: To assess if alterations in renal artery stenosis (RAS) during lactation

Implication of RAS in postnatal cardiac remodeling, fibrosis and dysfunction induced by fetal undernutrition Read More »

Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data

Nazmuddin M, Philippens IHCHM, van Laar T (2021) Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data. Sci Rep 11(1):11751. doi: 10.1038/s41598-021-91391-0 Objective: Review the design of stimulation experiments on the nucleus basalis of Meynert (NBM) and its effects on behavioral and neurophysiological aspects. Summary: Deep brain stimulation

Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data Read More »

Utilization of pectoralis minor accessory inspiratory muscles in a rodent model of respiratory motor neuron loss

Borkowski L, Nichols N (2021) Utilization of pectoralis minor accessory inspiratory muscles in a rodent model of respiratory motor neuron loss. FASEB J 35(S1) Experimental Biology 2021 Meeting Abstracts. doi: 10.1096/fasebj.2021.35.S1.01843 PMID: 0 Objective: To develop a model of selective respiratory motor neuron death to study how breathing is impacted and advance targeted therapeutic interventions.

Utilization of pectoralis minor accessory inspiratory muscles in a rodent model of respiratory motor neuron loss Read More »

Role of A1/A2 neurons in the dysregulation of vasopressin release and dilutional hyponatremia in liver disease

Aikins A, Little J, Cunningham, J (2021) Role of A1/A2 neurons in the dysregulation of vasopressin release and dilutional hyponatremia in liver disease. FASEB J 35(1) Experimental Biology 2021 Meeting Abstracts. doi: 10.1096/fasebj.2021.35.S1.04975 PMID: 0 Summary: Experiments suggest that A1/A2 neurons could be involved in the increased plasma AVP seen in male BDL rats as

Role of A1/A2 neurons in the dysregulation of vasopressin release and dilutional hyponatremia in liver disease Read More »

Tart cherry (fruit of prunus cerasus) concentrated powder (tccp) ameliorates glucocorticoid-induced muscular atrophy in mice.

Ku SK, Lim JM, Cho HR, Bashir KMI, Kim YS, Choi JS (2021) Tart cherry (fruit of prunus cerasus) concentrated powder (tccp) ameliorates glucocorticoid-induced muscular atrophy in mice. Medicina (Kaunas) 57(5):485. doi: 10.3390/medicina57050485 PMID: 34066110 Summary: Tart cherries have shown memory impairment lowering properties. Related Products: mu p75-SAP (Cat. #IT-16) See Also: Matchynski JJ et

Tart cherry (fruit of prunus cerasus) concentrated powder (tccp) ameliorates glucocorticoid-induced muscular atrophy in mice. Read More »

Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling

Kawanabe R, Yoshihara K, Hatada I, Tsuda M (2021) Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling. Mol Brain 14(1):79. doi: 10.1186/s13041-021-00788-5 Summary: Astrocytes are critical regulators of neuronal function in the central nervous system (CNS). Astrocytes in the spinal dorsal horn (SDH) increase intracellular Ca2+ levels following intraplantar injection

Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling Read More »

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