Kawasaki R, Sasaki Y, Nishimura T, Katagiri K, Morita KI, Sekine Y, Sawada SI, Mukai SA, Akiyoshi K (2021) Magnetically navigated protein transduction in vivo using iron oxide-nanogel chaperone hybrid. Adv Healthc Mater 10(9):e2001988. doi: 10.1002/adhm.202001988 Summary: A magnetically guided in vivo protein transduction is demonstrated using magnetic nanogel chaperone (MC) composed of iron oxide […]
Delarue Q, Robac A, Massardier R, Marie JP, Guérout N (2021) Comparison of the effects of two therapeutic strategies based on olfactory ensheathing cell transplantation and repetitive magnetic stimulation after spinal cord injury in female mice. J Neurosci Res 99(7):1835-1849. doi: 10.1002/jnr.24836 PMID: 33960512 Objective: To compare two therapeutic approaches; individual primary olfactory ensheathing cell
da Costa C, Soares JI, Lukoyanov NV (2021) Forebrain cholinergic plasticity in rats with chronic epilepsy induced by status epilepticus. . 14th U.PORTO Young Researchers Meeting Summary: This poster had the following aims: 1) Evaluate the GABAergic population in the MS/DB in a chronic epilepsy model of kainic acid (KA)-treated rats. 2) Assess the GABAergic
Kim HN, Kim JY (2021) A systematic review of oropharyngeal dysphagia models in rodents. Int J Environ Res Public Health 18(9):4987. doi: 10.3390/ijerph18094987 Objective: To organize the rodent models of oropharyngeal dysphagia reported to date. Summary: Applying and analyzing the treatment in rodent models of dysphagia induced from various causes is an essential process to
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Gonzalez EA, Leitão SAT, Dos Santos Soares D, Tavares AMV, Giugliani R, Baldo G, Matte U (2021) Cardiac pathology in Mucopolysaccharidosis I mice: Losartan modifies ERK1/2 activation during cardiac remodeling. J Inherit Metab Dis 44(3):740-750. doi: 10.1002/jimd.12327 PMID: 33145772 Objective: To investigate whether the pathways influenced by losartan and propranolol may modulate the cardiac remodeling
Madrid LI, Jimenez-Martin J, Coulson EJ, Jhaveri DJ (2021) Cholinergic regulation of adult hippocampal neurogenesis and hippocampus-dependent functions. Int J Biochem Cell Biol 134:105969. doi: 10.1016/j.biocel.2021.105969 Summary: In this review, the authors appraise the evidence linking the contribution of cholinergic signalling to the regulation of adult hippocampal neurogenesis and hippocampus-dependent functions. Usage: A hallmark feature
Ming X, Prasad N, Thulasi V, Elkins K, Shivamurthy VKN (2021) Possible contribution of cerebellar disinhibition in epilepsy. Epilepsy Behav 118:107944. doi: 10.1016/j.yebeh.2021.107944 Summary: The authors hypothesize that loss of inhibition from the cerebellum can lead to cortical activation and seizures. An animal study showed microinjection of SSP-SAP produced a selective ablation of hippocampal inhibitory
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Loftén A, Adermark L, Ericson M, Söderpalm B (2021) An acetylcholine-dopamine interaction in the nucleus accumbens and its involvement in ethanol’s dopamine-releasing effect. Addict Biol 26(3):e12959. doi: 10.1111/adb.12959 Summary: Basal extracellular levels of dopamine within the nucleus accumbens are not sustained by muscarinic acetylcholine, whereas accumbal Cholinergic interneurons-ACh are involved in mediating ethanol-induced dopamine release.
Penna S, Villa A, Capo V (2021) Autosomal recessive osteopetrosis: mechanisms and treatments. Dis Model Mech 14(5):dmm048940. doi: 10.1242/dmm.048940 Summary: Autosomal recessive osteopetrosis (ARO) is a severe inherited bone disease characterized by defective osteoclast resorption or differentiation. Novel therapeutic approaches are needed for ARO patients. The authors review preclinical and proof-of-concept studies, such as gene
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Polito L, Bortolotti M, Iglesias R, Bolognesi A (2021) Editorial: Toxic plant proteins as experimental drugs for human pathologies. Front Pharmacol 12:689924. doi: 10.3389/fphar.2021.689924 Related Products: Saporin (Cat. #PR-01)
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