Yuan H, Hu H, Chen R, Mu W, Wang L, Li Y, Chen Y, Ding X, Xi Y, Mao S, Jiang M, Chen J, He Y, Wang L, Dong Y, Tou J, Chen W (2021) Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine. Stem Cells Transl Med 10(6):922-938. doi: 10.1002/sctm.20-0469
Objective: To determine whether premigratory NCSCs (pNCSCs) could form enteric neurons and mediate the motility.
Summary: The results show that the pNCSCs that were previously assumed to not be induced by intestinal environment or cues can innervate the intestine and establish neuron-dependent motility.
Usage: Immunochemistry (1:200)
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