Author name: Kristen Hartman

Hartlage-Rübsamen M, Schliebs R (2001) Rat basal forebrain cholinergic lesion affects neuronal nitric oxide synthase activity in hippocampal and neocortical target regions. Brain Res 889(1-2):155-164. doi: 10.1016/s0006-8993(00)03128-0 Summary: Nitric oxide (NO) mediates a variety of mechanisms in the brain including cortical perfusion, learning and memory, and neuronal plasticity. Cholinergic dysfunction has been associated with some […]

Baxter MG (2001) Effects of selective immunotoxic lesions on learning and memory. (eds. Hall WA). In: Immunotoxin Methods and Protocols. Methods in Molecular Biology. 166:249-265. Humana Press. doi: 10.1385/1-59259-114-0:249 Summary: Dr. Baxter presents a brief review of studies using immunotoxins to study learning and memory. In particular, this chapter focuses on the use of 192-Saporin

Wiley RG (2001) Toxin-induced death of neurotrophin-sensitive neurons. (eds. Rush RA). In: Neurotrophin Protocols. Methods in Molecular Biology. 169:217-222. Humana Press. doi: 10.1385/1-59259-060-8:217 Summary: Wiley discusses some of the specifics of using 192-Saporin (Cat. #IT-01) to eliminate cells expressing the rat p75 low-affinity nerve growth factor receptor. Wiley also describes the sequence of events following

Beninger RJ, Dringenberg HC, Boegman RJ, Jhamandas K (2001) Cognitive effects of neurotoxic lesions of the nucleus basalis magnocellularis in rats: differential roles for corticopetal versus amygdalopetal projections. Neurotox Res 3(1):7-21. doi: 10.1007/BF03033227 Summary: The cholinergic hypothesis states that projections of cholinergic neurons from the nucleus basalis magnocellularis to cortical and amygdalar targets are important