Author name: Kristen Hartman

Olfaction, cholinergic basal forebrain degeneration, and cognition in early Parkinson disease

Barrett MJ, Murphy JM, Zhang J, Blair JC, Flanigan JL, Nawaz H, Dalrymple WA, Sperling SA, Patrie J, Druzgal TJ (2021) Olfaction, cholinergic basal forebrain degeneration, and cognition in early Parkinson disease. Parkinsonism Relat Disord 90:27-32. doi: 10.1016/j.parkreldis.2021.07.024 Summary: This study examined the relationship between olfaction, longitudinal change in cholinergic basal forebrain nuclei and their […]

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Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory

Soma S, Suematsu N, Sato AY, Tsunoda K, Bramian A, Reddy A, Takabatake K, Karube F, Fujiyama F, Shimegi S (2021) Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory. Neurobiol Learn Mem 183:107484. doi: 10.1016/j.nlm.2021.107484 Summary: The authors tested the effect of a cholinesterase inhibitor, donepezil, on the retrieval of memory

Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory Read More »

Cholinergic modulation of sensory processing in awake mouse cortex

Jimenez-Martin J, Potapov D, Potapov K, Knöpfel T, Empson RM (2021) Cholinergic modulation of sensory processing in awake mouse cortex. Sci Rep 11(1):17525. doi: 10.1038/s41598-021-96696-8 Objective: To decipher the timing and significance of acetylcholine actions. Summary: Study provides new insights into how the cortex processes sensory information and how loss of acetylcholine, for example in

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Divergent receptor utilization is necessary for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections

Borkowski LF, Smith CL, Keilholz AN, Nichols NL (2021) Divergent receptor utilization is necessary for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections. J Neurophysiol 126(3):709-722. doi: 10.1152/jn.00236.2021 Objective: The authors tested the hypothesis that phrenic long-term facilitation (pLTF) following treatment with CTB-SAP is: 1) adenosine 2A (A2A) receptor-dependent

Divergent receptor utilization is necessary for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections Read More »

Roles of the FGF-FGFR signaling system in cancer development and inflammation

Wiedlocha A, Haugsten EM, Zakrzewska M (2021) Roles of the FGF-FGFR signaling system in cancer development and inflammation. Cells 10(9):2231. doi: 10.3390/cells10092231 PMID: 34571880 Objective: To highlight the latest advances in understanding the role of the FGF-FGFR signaling system in the development of neoplastic diseases and in the induction and maintenance of inflammation and its

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Reduction of arcuate kappa-opioid receptor-expressing cells increased luteinizing hormone pulse frequency in female rats

Dai M, Nakamura S, Takahashi C, Sato M, Munetomo A, Magata F, Uenoyama Y, Tsukamura H, Matsuda F (2021) Reduction of arcuate kappa-opioid receptor-expressing cells increased luteinizing hormone pulse frequency in female rats. Endocr J 68(8):933-941. doi: 10.1507/endocrj.EJ20-0832 Summary: The number of Kiss1-expressing cells in the ARC was not affected by ARC Dyno-SAP treatment. Dynorphin-Kappa

Reduction of arcuate kappa-opioid receptor-expressing cells increased luteinizing hormone pulse frequency in female rats Read More »

Tetrahydrocurcumin ameliorates kidney injury and high systolic blood pressure in high-fat diet-induced type 2 diabetic mice

Sangartit W, Ha KB, Lee ES, Kim HM, Kukongviriyapan U, Lee EY, Chung CH (2021) Tetrahydrocurcumin ameliorates kidney injury and high systolic blood pressure in high-fat diet-induced type 2 diabetic mice. Endocrinol Metab (Seoul) 36(4):810-822. doi: 10.3803/EnM.2021.988 PMID: 34474516 Objective: To investigate the protective effect of tetrahydrocurcumin (THU) on intrarenal RAS expression, kidney injury, and

Tetrahydrocurcumin ameliorates kidney injury and high systolic blood pressure in high-fat diet-induced type 2 diabetic mice Read More »

Neuroscience 2021 and Targeting Trends

Targeting Topics /

Have you read Targeting Trends newsletters? Now in a more convenient format, the ATS newsletters are accessible on our website. Features include summaries of the latest publications, FAQ to answer product questions, and articles with cutting edge research shared by featured scientists. Plus cameo appearances by our beloved cats. Flip through the pages of the newsletters like

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Annual ATS Poster of the Year Winners

Meetings Abstracts /

Neuroscience 2019 Truckenbrod LM, Bumanglag AV, Chun E, Hernandez A, Federico QP, Maurer AP, Sloviter RS, Burke SN (2019) Targeted hippocampal GABA neuron ablation produces hippocampal sclerosis, epilepsy, and dissociable effects on the Morris water maze and object-place paired association tasks. Neuroscience 2019 Abstracts 158.03. Society for Neuroscience, Chicago, IL An epileptogenic role for hippocampal

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The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder

Han D, Shi Y, Han F (2022) The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder. J Comp Neurol 530(3):592-606. doi: 10.1002/cne.25231 Objective: To determine the role of the orexin system in mediating anxiety- and depression-related behaviors in PTSD. Summary: Intracerebroventricular administration of

The effects of orexin-A and orexin receptors on anxiety- and depression-related behaviors in a male rat model of post-traumatic stress disorder Read More »

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