Gilley D, Tanaka H, Herbert BS (2005) Telomere dysfunction in aging and cancer. Int J Biochem Cell Biol 37(5):1000-1013. doi: 10.1016/j.biocel.2004.09.003 PMID: 15743674 Related Products: TRF1 Mouse Monoclonal (Cat. #AB-37)
Telomere dysfunction in aging and cancer. Read More »
Lopez-Coviella I, Follettie MT, Mellott TJ, Kovacheva VP, Slack BE, Diesl V, Berse B, Thies RS, Blusztajn JK (2005) Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons. Proc Natl Acad Sci U S A 102(19):6984-6989. doi: 10.1073/pnas.0502097102 PMID: 15870197 Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01), NGFr (mu p75)
Winters BD, Bussey TJ (2005) Removal of cholinergic input to perirhinal cortex disrupts object recognition but not spatial working memory in the rat. Eur J Neurosci 21(8):2263-2270. doi: 10.1111/j.1460-9568.2005.04055.x Summary: The perirhinal cortex of the temporal lobe is crucial to object recognition memory. The authors examined the role of cholinergic input from the basal forebrain
Kuczewski N, Aztiria E, Leanza G, Domenici L (2005) Selective cholinergic immunolesioning affects synaptic plasticity in developing visual cortex. Eur J Neurosci 21(7):1807-1814. doi: 10.1111/j.1460-9568.2005.04014.x Summary: In this study the authors examined the role of subcortical cholinergic inputs in the regulation of plastic events in the visual cortex during early postnatal development. Four-day-old mouse pups
Ohara PT, Kelley K, Jasmin L (2005) B fragment of cholera toxin conjugated to saporin . (eds. Ronald GW, Douglas AL). Molecular Neruosurgery With Targeted Toxins 293-306. Humana. doi: 10.1007/978-1-59259-896-0_13 Summary: CTB-Saporin is a lesioning tool used to target GM1 ganglioside residues, which are highly expressed within certain nervous cell tissue. It distinguishes itself from
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One of the most important features of the Advanced Targeting Systems product line is the availability of control toxins that allow the researcher to fully evaluate results of the treatment of cells or animals with targeted toxins. For instance, anti-DBH-SAP is targeted with a mouse monoclonal antibody. Its control partner is mouse IgG-SAP, that is,
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Kondo I, Marvizon JC, Song B, Salgado F, Codeluppi S, Hua XY, Yaksh TL (2005) Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked substance P release. J Neurosci 25(14):3651-3660. doi: 10.1523/JNEUROSCI.0252-05.2005 PMID: 15814796 Related Products: Antibody to NK-1 Receptor (Cat. #AB-N04)
Q: We are re-examining some data collected using an immunotoxin not prepared by your company (VChAT-sap). Our results in vivo indicated that there were non-specific effects although the creators claimed it was specific. We ran a Western Blot and determined that about half the saporin was not bound to the antibody. This may have been
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Northrop LE, Cameron N, Erskine M (2005) Featured Article: Noradrenergic inputs to the medial amygdala originate in the A1 and A2 cells groups and release norepinephrine after mating stimulation sufficient to induce pseudopregnancy. Targeting Trends 6(2) Related Products: Anti-DBH-SAP (Cat. #IT-03) Read the featured article in Targeting Trends.
Mancuso M, Davidzon G, Kurlan RM, Tawil R, Bonilla E, Di Mauro S, Powers JM (2005) Hereditary ferritinopathy: a novel mutation, its cellular pathology, and pathogenetic insights. J Neuropathol Exp Neurol 64(4):280-294. doi: 10.1093/jnen/64.4.280 PMID: 15835264 Related Products: Malondialdehyde Rabbit Polyclonal, Conjugated (Cat. #AB-T090)