Ohara PT, Kelley K, Jasmin L (2005) B fragment of cholera toxin conjugated to saporin . (eds. Ronald GW, Douglas AL). Molecular Neruosurgery With Targeted Toxins 293-306. Humana. doi: 10.1007/978-1-59259-896-0_13
Summary: CTB-Saporin is a lesioning tool used to target GM1 ganglioside residues, which are highly expressed within certain nervous cell tissue. It distinguishes itself from other common saporin conjugates as it is most used not to lesion neurons but instead mylelin producing oligodendrocytes. CTB-SAP can be used to target these cells in order to study demyelination and remyelination in the spinal cord.
Related Products: CTB-SAP (Cat. #IT-14)