Author name: Kristen Hartman

Cholinergic modulation of sensory interference in rat primary somatosensory cortical neurons.

Alenda A, Nunez A (2007) Cholinergic modulation of sensory interference in rat primary somatosensory cortical neurons. Brain Res 1133:158-167. doi: 10.1016/j.brainres.2006.11.092 Summary: One critical feature of cognition is the ability to focus on selected sensory inputs while ignoring irrelevant inputs. In this work the authors examine basal forebrain participation in sensory interference effects. Following 0.15 […]

Cholinergic modulation of sensory interference in rat primary somatosensory cortical neurons. Read More »

Selective cholinergic depletion of the hippocampus spares both behaviorally induced Arc transcription and spatial learning and memory.

Fletcher BR, Baxter MG, Guzowski JF, Shapiro ML, Rapp PR (2007) Selective cholinergic depletion of the hippocampus spares both behaviorally induced Arc transcription and spatial learning and memory. Hippocampus 17:227-234. doi: 10.1002/hipo.20261 Summary: The immediate early gene Arc is required for long-term synaptic changes and memory consolidation. The authors lesioned the fornix to examine cholinergic

Selective cholinergic depletion of the hippocampus spares both behaviorally induced Arc transcription and spatial learning and memory. Read More »

Dissociation of attention in learning and action: effects of lesions of the amygdala central nucleus, medial prefrontal cortex, and posterior parietal cortex

Maddux JM, Kerfoot EC, Chatterjee S, Holland PC (2007) Dissociation of attention in learning and action: effects of lesions of the amygdala central nucleus, medial prefrontal cortex, and posterior parietal cortex. Behav Neurosci 121(1):63-79. doi: 10.1037/0735-7044.121.1.63 Objective: To study the effect of the amygdala central nucleus (CEA) on aspects of attention. Summary: Lesions of the

Dissociation of attention in learning and action: effects of lesions of the amygdala central nucleus, medial prefrontal cortex, and posterior parietal cortex Read More »

From anxiety to autism: spectrum of abnormal social behaviors modeled by progressive disruption of inhibitory neuronal function in the basolateral amygdala in Wistar rats.

Truitt WA, Sajdyk TJ, Dietrich AD, Oberlin B, McDougle CJ, Shekhar A (2007) From anxiety to autism: spectrum of abnormal social behaviors modeled by progressive disruption of inhibitory neuronal function in the basolateral amygdala in Wistar rats. Psychopharmacology (Berl) 191(1):107-118. doi: 10.1007/s00213-006-0674-y Summary: The amygdala has been identified as being involved in social behaviors. Six

From anxiety to autism: spectrum of abnormal social behaviors modeled by progressive disruption of inhibitory neuronal function in the basolateral amygdala in Wistar rats. Read More »

Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells.

Yip WL, Weyergang A, Berg K, Tonnesen HH, Selbo PK (2007) Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells. Mol Pharm 4(2):241-251. doi: 10.1021/mp060105u Summary: Photochemical internalization (PCI) releases macromolecules from endocytic vesicles using photosensitizer activation by light. This technique allows the release of endocytosed molecules before degradation occurs

Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells. Read More »

P2Y1 receptor modulation of the pre-Bötzinger complex inspiratory rhythm generating network in vitro.

Lorier AR, Huxtable AG, Robinson DM, Lipski J, Housley GD, Funk GD (2007) P2Y1 receptor modulation of the pre-Bötzinger complex inspiratory rhythm generating network in vitro. J Neurosci 27(5):993-1005. doi: 10.1523/JNEUROSCI.3948-06.2007 PMID: 17267553 Related Products: Antibody to NK-1 Receptor (Cat. #AB-N04)

P2Y1 receptor modulation of the pre-Bötzinger complex inspiratory rhythm generating network in vitro. Read More »

Neurotoxic lesions centered on the perifornical hypothalamus abolish the cardiovascular and behavioral responses of conditioned fear to context but not of restraint.

Furlong T, Carrive P (2007) Neurotoxic lesions centered on the perifornical hypothalamus abolish the cardiovascular and behavioral responses of conditioned fear to context but not of restraint. Brain Res 1128(1):107-119. doi: 10.1016/j.brainres.2006.10.058 Summary: This work examined the role of orexin-containing neurons in the perifornical hypothalamus (PeF) during stress response. Orexin-SAP (Cat. #IT-20) or the control

Neurotoxic lesions centered on the perifornical hypothalamus abolish the cardiovascular and behavioral responses of conditioned fear to context but not of restraint. Read More »

Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism.

Walker BR, Diefenbach KS, Parikh TN (2007) Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism. Behav Brain Res 176(1):109-120. doi: 10.1016/j.bbr.2006.08.008 Summary: In this work the authors use environmental exploration deficits in rats as a model for autism. Animals received 2 µg

Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism. Read More »

Noncholinergic lesions of the medial septum impair sequential learning of different spatial locations.

Dwyer TA, Servatius RJ, Pang KC (2007) Noncholinergic lesions of the medial septum impair sequential learning of different spatial locations. J Neurosci 27:299-303. doi: 10.1523/JNEUROSCI.4189-06.2007 Summary: The medial septum and the vertical limb of the diagonal band of Broca (MSDB) have extensive connections to the hippocampus. In general, impairments due to loss of cholinergic neurons

Noncholinergic lesions of the medial septum impair sequential learning of different spatial locations. Read More »

Targeting Tools: Anti-CRH/CRF

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Anti-CRH/CRF, Cat. #AB-02 Corticotropin-releasing hormone/factor (CRH/CRF) is the principal neuropeptide involved in regulating the stress response. It stimulates ACTH release from the pituitary gland. When centrally administered to animals it produces somatic changes analogous to those seen in both depression and anxiety. In humans, it is capable of reproducing the hormonal changes which are characteristically

Targeting Tools: Anti-CRH/CRF Read More »

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