Author name: Kristen Hartman

Targeting Tools: Anti-Conjugated Glutathione

Anti-Conjugated Glutathione, Cat. #AB-T01 Glutathione is a small protein composed of three amino acids: cysteine, glutamic acid, and glycine. The primary biological function of glutathione is to act as a non-enzymatic reducing agent. Glutathione is also involved in detoxification. Anti-Conjugated Glutathione targets conjugated glutathione which is created by fixation in glutaraldehyde. Applications include ELISA and […]

Targeting Tools: Anti-Conjugated Glutathione Read More »

Targeting Tools: Anti-Conjugated Acetylcholine

Anti-Conjugated Acetylcholine, Cat. #AB-T02 Acetylcholine is a neurotransmitter found in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans. Anti-Conjugated Acetylcholine targets conjugated choline-glutaric acid which is created by fixation in glutaraldehyde. Applications include ELISA and immunohistochemistry.

Targeting Tools: Anti-Conjugated Acetylcholine Read More »

Targeting Tools: Anti-Conjugated Dopamine

Anti-Conjugated Dopamine, Cat. #AB-T11 Dopamine is a neurotransmitter found in various areas of the central and peripheral nervous system. Dopamine and its agonists play an important role in cardiovascular, renal, hormonal, and central nervous system regulation. Anti-Conjugated Dopamine targets conjugated dopamine which is created by fixation in glutaraldehyde. Applications include ELISA, immunocytochemistry, immunohistochemistry, and immunoblotting.

Targeting Tools: Anti-Conjugated Dopamine Read More »

Targeting Tools: Anti-CRH/CRF

Anti-CRH/CRF, Cat. #AB-02 Corticotropin-releasing hormone/factor (CRH/CRF) is the principal neuropeptide involved in regulating the stress response. It stimulates ACTH release from the pituitary gland. When centrally administered to animals it produces somatic changes analogous to those seen in both depression and anxiety. In humans, it is capable of reproducing the hormonal changes which are characteristically

Targeting Tools: Anti-CRH/CRF Read More »

Targeted Toxin Controls

Q: Your targeted toxin kits come with different controls. I’m not sure of the best way to use them. For example, with the anti-SERT-SAP kit (Cat. # KIT-23) there is included unconjugated antibody, unconjugated saporin, and a control conjugate, mouse IgG-SAP. Should I use them all in the same experiment or for different purposes? A:

Targeted Toxin Controls Read More »

Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from alpha2-adrenoceptor stimulation.

Ma W, Eisenach JC (2007) Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from alpha2-adrenoceptor stimulation. Brain Res 1127(1):52-58. doi: 10.1016/j.brainres.2006.10.008 Summary: Peripheral nerve injury resulting in neuropathic pain often responds poorly to opioid treatment. alpha2-adrenoreceptor (AR) agonists, however, perform better after

Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from alpha2-adrenoceptor stimulation. Read More »

Featured Article: Cholinergic immunolesioning produced tangle-like inclusions in TgCRND8 brain

Chauhan N (2007) Featured Article: Cholinergic immunolesioning produced tangle-like inclusions in TgCRND8 brain. Targeting Trends 8(1) Related Products: mu p75-SAP (Cat. #IT-16) Read the featured article in Targeting Trends. See Also: Chauhan NB Cholinergic immunolesioning produced tangle-like inclusions in TgCRND8 brain. Neuroscience 2006 Abstracts 271.8, 2006. Society for Neuroscience, Atlanta, GA

Featured Article: Cholinergic immunolesioning produced tangle-like inclusions in TgCRND8 brain Read More »

Cover Article: Cholinergic Immunolesioning Produced Tangle-like Inclusions in TgCRND8 Brain

Contributed by Neelima Chauhan, Dept Anesthes/Anat & Cell Bio, Univ Illinois-Chicago;J. Brown VA Med Ctr Chicago, Chicago, IL and winner of the 2006 SfN Poster Award for work using ATS products. Today’s Alzheimer’s disease (AD) research lacks a “complete” model that would represent both plaque and tangle pathology together with correlative memory deficits. The currently

Cover Article: Cholinergic Immunolesioning Produced Tangle-like Inclusions in TgCRND8 Brain Read More »

Low doses of antigen coupled to anti-CR2 mAbs induce rapid and enduring IgG immune responses in mice and in cynomolgus monkeys

Whipple EC, Ditto AH, Shanahan RS, Gatesman JJ, Little SF, Taylor RP, Lindorfer MA (2007) Low doses of antigen coupled to anti-CR2 mAbs induce rapid and enduring IgG immune responses in mice and in cynomolgus monkeys. Mol Immunol 44(4):377-388. doi: 10.1016/j.molimm.2006.02.032 PMID: 16631928 Related Products: Antibody to Complement C3 (10C7) (Cat. #AB-V80)

Low doses of antigen coupled to anti-CR2 mAbs induce rapid and enduring IgG immune responses in mice and in cynomolgus monkeys Read More »

Shopping Cart
Scroll to Top