Jeffry J, Kim S, Chen ZF (2011) Itch signaling in the nervous system. Physiology (Bethesda) 26(4):286-92. doi: 10.1152/physiol.00007.2011 Summary: This review examines recent work done to elucidate the molecular mechanisms behind the sensation of itch. The progress of mouse genetics has allowed the field to move beyond clinical and physiological studies, toward a better understanding […]
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Burke PG, Neale J, Korim WS, McMullan S, Goodchild AK (2011) Patterning of somatosympathetic reflexes reveals nonuniform organization of presympathetic drive from C1 and non-C1 RVLM neurons. Am J Physiol Regul Integr Comp Physiol 301(4):R1112-R1122. doi: 10.1152/ajpregu.00131.2011 Summary: Some neurons in the rostral ventrolateral medulla are part of the circuitry that helps maintain blood pressure.
Chen S, Badea T, Hattar S (2011) Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs. Nature 476:92-95. doi: 10.1038/nature10206 PMID: 21765429 Summary: Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment Melanopsin and regulate a wide array of light dependent physiological processes. Genetic ablation of ipRGCs eliminates circadian photoentrainment and severely
Gulino R, Gulisano M (2011) A central role for BDNF and Sonic Hedgehog in controlling synaptic plasticity in motoneuron-depleted spinal cord. IBRO 2011 Abstracts International Brain Research Organization, Florence, Italy. Summary: Here, we measured the expression levels of several proteins involved in synaptic plasticity and motoneuronal function (ChAT, Synapsin-I, Shh, Notch-1, AMPA receptor subunits, NMDA
Roach EB, Hussain Shuler MG (2011) Cholinergic denervation disrupts temporal learning in rodent visual cortex. IBRO 2011 Abstracts International Brain Research Organization, Florence, Italy. Summary: Local cholinergic terminals were removed using the selective neurotoxin 192 IgG-saporin between contingency reversal. This manipulation tested the necessity of cholinergic innervation in two key processes: expressing previously learned reward
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Ljubojevic V, Luu P, De Rosa E (2011) The role of cholinergic cortical modulation in visual and olfactory attention using the 5-Choice serial reaction time task. IBRO 2011 Abstracts International Brain Research Organization, Florence, Italy. Summary: After successful acquisition of both visual and olfactory task, the rats were subjected to either a cholinergic immunotoxic or
Bajo Lorenzana VM Leach ND, Cordery PM, Nodal FR, King AJ (2011) The cholinergic basal forebrain in the ferret and its inputs to the auditory cortex. IBRO 2011 Abstracts International Brain Research Organization, Florence, Italy. Summary: Projections from the NB to the auditory cortex were investigated by injecting tracers into the NB itself (n=5), or
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Facciabene A, Peng X, Hagemann IS, Balint K, Barchetti A, Wang L-P, Gimotty PA, Gilks CB, Lal P, Zhang L, Coukos G (2011) Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells. Nature 475:226-230. doi: 10.1038/nature10169 PMID: 21753853 Objective: To investigate whether a direct link between tumor hypoxia and tolerance occurs through the
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Reynolds J, Bilsky EJ, Meng ID (2011) Selective ablation of mu-opioid receptor expressing neurons in the rostral ventromedial medulla attenuates stress-induced mechanical hypersensitivity. Life Sci 89(9-10):313-9. doi: 10.1016/j.lfs.2011.06.024 Summary: Animals have been shown to develop hyperalgesia in response to chronic stress. Recent data has implicated the rostroventromedial medulla (RVM) in this process. In order to