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Cholinergic denervation disrupts temporal learning in rodent visual cortex

Roach EB, Hussain Shuler MG (2011) Cholinergic denervation disrupts temporal learning in rodent visual cortex. IBRO 2011 Abstracts International Brain Research Organization, Florence, Italy.

Summary: Local cholinergic terminals were removed using the selective neurotoxin 192 IgG-saporin between contingency reversal. This manipulation tested the necessity of cholinergic innervation in two key processes: expressing previously learned reward timing and shifting reward timing to new behaviorally relevant intervals.

Related Products: 192-IgG-SAP (Cat. #IT-01)