Abstracts from Society for Neuroscience (SFN) November 12-16, 2011 • Washington, DC
Abstracts from Society for Neuroscience (SFN) November 12-16, 2011 • Washington, DC Read More »
SFN Poster of the Year 2011
Awarded by ATS at Society for Neuroscience (SFN) November 12-16, 2011 • Washington, DC Be sure to check out the featured article in Targeting Trends. 712.07 Arcuate NK3 receptor-expressing KNDy neurons are essential for estrogen modulation of LH secretion and body weight in the female ratM A Smith, H Williams, S J Krajewski, N T Mcmullen,
SFN Poster of the Year 2011 Read More »
Highly selective lesion of the cholinergic pedunculopontine neurons using a minimally-invasive angular stereotaxic surgery with the Diphteria-Urotensin-II neurotoxin in rat
Cyr, M Maclaren DA, Bédard M-A, Clark SD, Mechawar N, Rochford J, Winn P (2011) Highly selective lesion of the cholinergic pedunculopontine neurons using a minimally-invasive angular stereotaxic surgery with the Diphteria-Urotensin-II neurotoxin in rat. Neuroscience 2011 Abstracts 37.06. Society for Neuroscience, Washington, DC. Summary: Highly selective cholinergic lesions of the basal forebrain can be
[18F] fluoroethoxybenzovesamicol (FEOBV): A reliable PET radiocompound for the in-vivo assessment of cholinergic terminals.
Parent M, Rosa-Neto P, Aliaga A, Soucy J-P, Bedard M-A (2011) [18F] fluoroethoxybenzovesamicol (FEOBV): A reliable PET radiocompound for the in-vivo assessment of cholinergic terminals. Neuroscience 2011 Abstracts 37.13. Society for Neuroscience, Washington, DC. Summary: The vesicular acetylcholine transporter (VAChT) can be used as a surrogate target for PET imaging of brain cholinergic terminals. [18F]fluoroethoxybenzovesamicol
Rapid beta-amyloid deposition and behavioural impairment after cholinergic denervation in APPswe/PS1dE9
Pacheco-Herrero M, Thyssen D, Ramos-Rodriguez J, Berrocoso E, Bacskai B, Garcia-Alloza M (2011) Rapid beta-amyloid deposition and behavioural impairment after cholinergic denervation in APPswe/PS1dE9. Neuroscience 2011 Abstracts 47.02. Society for Neuroscience, Washington, DC. Summary: Alzheimer’s disease (AD) is the most common cause of dementia. Although the ultimate neurotoxic mechanisms are not known, extensive evidence supports
Diminished norepinephrine release in the BSTv decreases anxiety but does not promote maternal behavior in nulliparous female rats.
Holschbach MA, Lonstein JS (2011) Diminished norepinephrine release in the BSTv decreases anxiety but does not promote maternal behavior in nulliparous female rats. Neuroscience 2011 Abstracts 86.06. Society for Neuroscience, Washington, DC. Summary: Postpartum caregiving heavily depends on both increased motivation to interact with offspring and decreased emotional reactivity. The early postpartum period is associated
Basal metabolic substrate utilization is altered by lesion of hindbrain catecholamine neurons that innervate the medial hypothalamus and substrate selection during glucoprivation is impaired.
Ritter S, Li A-J, Wang Q, Dinh TT (2011) Basal metabolic substrate utilization is altered by lesion of hindbrain catecholamine neurons that innervate the medial hypothalamus and substrate selection during glucoprivation is impaired. Neuroscience 2011 Abstracts 88.05. Society for Neuroscience, Washington, DC. Summary: Central injection of the targeted immunotoxin, anti-dopamine beta hydroxylase (DBH)-saporin (DSAP), retrogradely
Impaired social interaction and enhanced sensitivity to phencyclidine-induced deficits in novel object recognition in rats with cortical cholinergic denervation.
Savage S, Kehr J, Olson L, Mattsson A (2011) Impaired social interaction and enhanced sensitivity to phencyclidine-induced deficits in novel object recognition in rats with cortical cholinergic denervation. Neuroscience 195:60-69. doi: 10.1016/j.neuroscience.2011.08.027 Summary: Forebrain cholinergic dysfunction is thought to be part of the pathophysiology of schizophrenia. The authors lesioned the cholinergic corticopetal projection of rats
Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats.
Abbott SB, Stornetta RL, Coates MB, Guyenet PG (2011) Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats. J Neurosci 31(45):16410-16422. doi: 10.1523/JNEUROSCI.3280-11.2011 Summary: Neurons in the retrotrapezoid nucleus (RTN) are involved in the CO2-dependent control of breathing in conscious and anesthetized rats. In this work the authors specifically
Cholinergic modulation of a specific memory function of prefrontal cortex.
Croxson PL, Kyriazis DA, Baxter MG (2011) Cholinergic modulation of a specific memory function of prefrontal cortex. Nat Neurosci 14(12):1510-1512. doi: 10.1038/nn.2971 Summary: The authors investigated loss of acetylcholine in the large and highly differentiated PFC’s of rhesus monkeys. The monkeys received 80-92 20-ng injections of ME20.4-SAP (Cat. #IT-15) per hemisphere. Lesioned animals were severely
Cholinergic modulation of a specific memory function of prefrontal cortex. Read More »