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Redefining the components of central CO2 chemosensitivity – towards a better understanding of mechanism.

Huckstepp RT, Dale N (2011) Redefining the components of central CO2 chemosensitivity – towards a better understanding of mechanism. J Physiol 589(Pt 23):5561-5579. doi: 10.1113/jphysiol.2011.214759

Summary: This review discusses advances in the field of CO2 chemosensitivity over the past few years. Discussion of the role that locus coeruleus (LC) neurons play in this process describe the use of anti-DBH-SAP (Cat. #IT-03) to reduce the hypercapnic ventilatory response. Data from these and other experiments support a role of the LC in modulation of the ventilatory response to hypercapnia.

Related Products: Anti-DBH-SAP (Cat. #IT-03)