Damelin M, Bankovich A, Park A, Aguilar J, Anderson W, Santaguida M, Aujay M, Fong S, Khandke K, Pulito V, Ernstoff E, Escarpe P, Bernstein J, Pysz M, Zhong W, Upeslacis E, Lucas J, Lucas J, Nichols T, Loving K, Foord O, Hampl J, Stull R, Barletta F, Falahatpisheh H, Sapra P, Gerber H, Dylla […]
Kras J, Weisshaar C, Pall P, Winkelstein B (2015) Pain from intra-articular NGF or joint injury in the rat requires contributions from peptidergic joint afferents. Neurosci Lett 604:193-198. doi: 10.1016/j.neulet.2015.07.043 Summary: Both peptidergic and non-peptidergic neurons innervate the facet joint, which is the source of pain in a majority of neck trauma. In this work
Araldi D, Ferrari L, Levine J (2015) Repeated mu-opioid exposure induces a novel form of the hyperalgesic priming model for transition to chronic pain. J Neurosci 35:12502-12517. doi: 10.1523/JNEUROSCI.1673-15.2015 Summary: Repeated administration of mu-opioid receptor agonists can lead to persistent mechanical hyperalgesia. One current hypothesis is that a form of hyperalgesic priming is triggered by
Saeed A, Pawlowski S, Ribeiro-da-Silva A (2015) Limited changes in spinal lamina I dorsal horn neurons following the cytotoxic ablation of non-peptidergic C-fibers. Mol Pain 11:54. doi: 10.1186/s12990-015-0060-z Summary: For the most part nociceptive information is moved from the periphery to the spinal cord through small diameter primary afferents. One subclass of these afferents is
Apps R, Strata P (2015) Neuronal circuits for fear and anxiety – the missing link. Nat Rev Neurosci 16(10):642. doi: 10.1038/nrn4028 PMID: 26333516 Objective: To study the active role of the cerebellar network in conditioned and unconditioned fear by quantifying the connection of cerebellar cortical areas to emotional driven responses. Summary: The article seeks to
Neuronal circuits for fear and anxiety – the missing link Read More »
Murray R, Logan M, Horner K (2015) Striatal patch compartment lesions reduce stereotypy following repeated cocaine administration. Brain Res 1618:286-298. doi: 10.1016/j.brainres.2015.06.012 PMID: 26100338 Objective: Investigate the impact of neuron ablation in the striatum on stereotypy, a form of repetitive and uncontrollable behavior, in rats following cocaine administration. Summary: Stereotypy, characterized by rigid, repetitive behaviors
Li A, Wang Q, Davis H, Wang R, Ritter S (2015) Orexin-A enhances feeding in male rats by activating hindbrain catecholamine neurons. Am J Physiol Regul Integr Comp Physiol 309:R358-367. doi: 10.1152/ajpregu.00065.2015 Summary: Although administration of orexin, norepinephrine, and epinephrine all induce significantly increased food intake, the potential interaction between the networks affected by these
Orexin-A enhances feeding in male rats by activating hindbrain catecholamine neurons. Read More »
McHugh S, Francis A, McAuley J, Stewart A, Baxter M, Bannerman D (2015) Hippocampal acetylcholine depletion has no effect on anxiety, spatial novelty preference, or differential reward for low rates of responding (DRL) performance in rats. Behav Neurosci 129:491-501. doi: 10.1037/bne0000072 Summary: It is unclear whether cholinergic lesions in the hippocampus affect both learning and
Li J, Pan Y, Zhang B, Chen Q (2015) Macrophages are needed in the progression of tuberculosis into lung cancer. Tumour Biol 36:6063-6066. doi: 10.1007/s13277-015-3283-8 Summary: Approximately 30% of lung carcinomas also have tuberculosis lesions. The authors investigated the potential link between inflammatory processes and cancer in the lung. Mice with established tuberculosis infections received
Macrophages are needed in the progression of tuberculosis into lung cancer. Read More »
Xing D, Wu Y, Li G, Song S, Liu Y, Liu H, Wang X, Fei Y, Zhang C, Li Y, Zhang L (2015) Role of cerebrospinal fluid-contacting nucleus in sodium sensing and sodium appetite. Physiol Behav 147:291-299. doi: 10.1016/j.physbeh.2015.04.034 Summary: Sodium concentration in the cerebrospinal fluid (CSF) is tightly regulated, and this regulation requires numerous
Role of cerebrospinal fluid-contacting nucleus in sodium sensing and sodium appetite. Read More »