ATS is in Booth 114 at the Alzheimer’s Association International Conference in London this week. Did you know that table tennis is widely reported to be an effective therapy for patients with Alzheimer’s Disease? This was news to us, but made us even more happy for ATS associates to be playing every Friday afternoon. Check […]
Table Tennis Therapy for Alzheimer’s Disease Read More »
Fu C, Xue J, Wang R, Chen J, Ma L, Liu Y, Wang X, Guo F, Zhang Y, Zhang X, Wang S (2017) Chemosensitive Phox2b-expressing neurons are crucial for hypercapnic ventilatory response in the nucleus tractus solitarius. J Physiol 595:4973-4989.. doi: 10.1113/JP274437 Objective: To investigate whether paired-like homeobox 2b (Phox2b)-expressing NTS neurons are recruited in
Brick, R (2017) Induced pluripotent stem cell-derived mesenchymal progenitor cells: Promotion of neuritogenesis and axon elongation through neurotrophin and cytokine production. University of Pittsburgh Thesis. Objective: To test if mesenchymal progenitor cells (MiMPCs), originally derived from mesenchymal stem cells (MSCs), have the same ability to support neuronal regeneration as the parent MSC. Summary: Results show
Cholinergic input to the hippocampus is not required for episodic memory in the rat, even with multiple consecutive events.S. Seel, M.J. Eacott, A. Easton. Behav Brain Res 2017. PMID: 28601587 The authors use 192-IgG-SAP (Cat. #IT-01) to examine episodic memory. Continual trials versions of an episodic memory task are unimpaired by cholinergic lesions of the medial septum. In contrast continual
192-IgG-SAP to Examine Episodic Memory Read More »
Q: Your targeted toxin kits come with different controls. I’m not sure of the best way to use them; there is included unconjugated antibody, unconjugated saporin, and a control conjugate, mouse IgG-SAP. Should I use them all in the same experiment or for different purposes? A: For mouse IgG-containing conjugates, the ideal control is Mouse
Using Kit Controls Read More »
Lai FP, Lau ST, Wong JK, Gui H, Wang RX, Zhou T, Lai WH, Tse HF, Tam PK, Garcia-Barcelo MM, Ngan ES (2017) Correction of Hirschsprung-associated mutations in human induced pluripotent stem cells via clustered regularly interspaced short palindromic repeats/cas9, restores neural crest cell function. Gastroenterology 153(1):139-153.e8. doi: 10.1053/j.gastro.2017.03.014 PMID: 28342760 Objective: To identify mutations
Casciello F, Al-Ejeh F, Kelly G, Brennan D, Ngiow S, Young A, Stoll T, Windloch K, Hill M, Smyth M, Gannon F, Lee J (2017) G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis. Proc Natl Acad Sci U S A 114:7077-7082. doi: 10.1073/pnas.1618706114 PMID: 28630300 Usage: Western blot Related Products: Trans-4-Hydroxy-L-Proline
Yaksh T, Fisher C, Hockman T, Wiese A (2017) Current and future issues in the development of spinal agents for the management of pain. Curr Neuropharmacol 15:232-259.. doi: 10.2174/1570159×14666160307145542 Summary: Although conscious pain experience is driven by signals mediated supraspinally, the more high intensity pain generated by strong stimuli, tissue injury, and nerve injury is
Taxini CL, Moreira TS, Takakura AC, Bicego KC, Gargaglioni LH, Zoccal DB (2017) Role of A5 noradrenergic neurons in the chemoreflex control of respiratory and sympathetic activities in unanesthetized conditions. Neuroscience 354:146-157.. doi: 10.1016/j.neuroscience.2017.04.033 Summary: The authors utilize Anti-DBH-SAP (Cat. #IT-03) to investigate the involvement of the A5 noradrenergic neurons to the basal and chemoreflex
Sonic Hedgehog and TDP-43 Participate in the Spontaneous Locomotor Recovery in a Mouse Model of Spinal Motoneuron Disease. Rosario Gulino *, Rosalba Parenti and Massimo Gulisano J. Funct. Morphol. Kinesiol. 2017, 2(2), 11; doi:10.3390/jfmk2020011 The authors used a mouse model of neurotoxic motoneuron depletion to study the role of Sonic hedgehog and TDP-43 in the compensatory changes occurring
Sonic Hedgehog and Beta Products Read More »