Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page. Newsletter Highlights ZAP Antibody Internalization Kit (page 2) Teaser Winners (page 2) Recent Scientific References (page 3) Product Q&A (page 5) Complete and Submit the Targeting Teaser …
Welcome to little Kermit. He knows he has Gangsta’s big paws to fill, but Kermit seems to be trying his best!
Screening large numbers of antibodies for the ability to internalize can be prohibitively expensive in both cost and time. The ZAP Antibody Internalization Kit contains all the components needed for three 96-well plates, or 288 tests. The ability to perform a diagnostic screen that is amenable to high-throughput methods, prior to direct conjugation of those …
I ordered the Streptavidin-ZAP (Cat. #IT-27) and had my antibody biotinylated a couple of months ago. I am ready to begin the first round of experiments to determine the concentration needed for the secondary. How much of the biotinylated antibody should I put to combine with the streptavidin for intravitreal injections? Can you please send …
Targeting Talk: Streptavidin-ZAP protocols and references Read More »
Role for monocyte chemoattractant protein-1 in the induction of chronic muscle pain in the rat. Alvarez P, Green PG, Levine JD. Pain 155(6):1161-1167, 2014. In order to better understand where monocyte chemoattractant protein 1 (MCP-1) fits in the chronic pain landscape the authors performed a series of experiments using antisense and mismatch oligodeoxynucleotides against the …
Contributed by Corinne Liying Lee, Ramamoorthy Rajkumar, Gavin Stewart Dawe, Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System; Neurobiology and Ageing Programme, Life Sciences Institute, National University of Singapore; and Singapore Institute for Neurotechnology (SINAPSE), Singapore 117456 The nucleus incertus (NI) is a distinct group of cells in the pontine …