Targeting Trends 2014 Newsletter
Read the 2014 Newsletters and recent scientific references 2014, issue 1: 2014, issue 2: 2014, issue 3: 2014, issue 4:
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Targeting Tools: Investigating the Itch Pathway
Bombesin-SAP (Cat. #IT-40) Bombesin is a 14-amino-acid peptide found in frog-skin. The human equivalent, gastrin releasing peptide (GRP) has been detected in itch pathways and plays a role in eating behaviors. GRP regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.
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Cover Article: FDA Gives Green Light to Human Clinical Trials for Cancer Pain
Contributed by Douglas A. Lappi, Ph.D., President/Chief Scientific Officer, Advanced Targeting Systems, San Diego, CA Substance P-Saporin (SP-SAP), ATS’s patented conjugate being developed for cancer pain therapy, has attracted a considerable amount of attention recently. Back-to-back publications, a press release and editorial were featured in the November issue of the journal Anesthesiology. The first article,
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