Read the 2014 Newsletters and recent scientific references 2014, issue 1: FDA Gives Green Light to Human Clinical Trials for Cancer Pain / by DA Lappi / featuring SP-SAP Targeting Talk: Time Course Targeting Tools: Investigating the Itch Pathway 2014, issue 2: Celebrating Twenty Years of Science Advanced Targeting Systems (founded 22 Apr 1994) / featuring 192-IgG-SAP, SP-SAP, Bombesin-SAP …
Bombesin-SAP (Cat. #IT-40) Bombesin is a 14-amino-acid peptide found in frog-skin. The human equivalent, gastrin releasing peptide (GRP) has been detected in itch pathways and plays a role in eating behaviors. GRP regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. …
Contributed by Douglas A. Lappi, Ph.D., President/Chief Scientific Officer, Advanced Targeting Systems, San Diego, CA Substance P-Saporin (SP-SAP), ATS’s patented conjugate being developed for cancer pain therapy, has attracted a considerable amount of attention recently. Back-to-back publications, a press release and editorial were featured in the November issue of the journal Anesthesiology. The first article, …
Cover Article: FDA Gives Green Light to Human Clinical Trials for Cancer Pain Read More »