11q4

Targeting Trends 2011 Newsletter

2011, issue 1: Targeted Lesion of Caudal Brainstem Catecholamine Neurons Reveals Their Role in Symptoms of Fatigue / by Goehler LE, Gaykema RPA / featuring Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18) SFN Poster of the Year Targeting Talk: Product Questions Targeting Tools: Anti-DBH-SAP (Cat. #IT-03) targets dopamine beta-hydroxylase 2011, issue 2: Carrageenan evoked P-Akt in deep …

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Targeting Topics 11q4

Galanin receptor-expressing dorsal horn neurons: Role in nociception. Lemons LL, Wiley RG. Neuropeptides Epub, August 2011. This work examines the nociceptive role of galanin receptor-1-expressing neurons found in the superficial dorsal horn. 500 ng of galanin-SAP (Cat. #IT-34) was injected into the lumbar intrathecal space of rats; blank-SAP (Cat. #IT-21) was used as a control. …

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Cover Article: Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity

Contributed by Tamara King and Frank Porreca Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA A common symptom of patients with neuropathic pain is spontaneous pain, often described as burning. Some patients also suffer from pain elicited by normally non-noxious stimuli, such as touch, referred to as allodynia. Preclinical studies have …

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