05q4

Targeting Trends Newsletter 05q4

Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page. Newsletter Highlights Spring Brain Meeting (page 2) Teaser Winners (page 2) Take Me Out to the Ballgame (page 6) Cy3-labeled anti-murine NGFr (page 7) Page 1 Page …

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Targeting Talk: Dose Ranging

We just completed surgeries where we implanted third ventricular cannulas and temporary bilatera cannulas directed into the nucleus tractus solitarius in the brainstem of animals. We injected either the Blank-SAP control toxin (Cat. #IT-21) or the experimental material Oxytocin-SAP into the bilateral NTS cannulae over a 30-second period. However, within the next week — two …

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Targeting Topics 05q4

Elimination of neurokinin-1 receptor neurons in caudal nucleus reverses the effects of systemic bicuculline on c-Fos expression in rat trigeminal sensory nucleus: I. High intensity electrical stimulation of the trigeminal ganglion. Abe T, Ohshita N, Sugiyo S, Moritani M, Kobayashi M, Takemura M. Neuroscience 133(3):739-747, 2005. The authors investigated the role of NK-1r + neurons …

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Cover Article: Effects of Intraseptal Orexin-Saporin on Spatial Memory

Contributed by Kevin Pang and Heidi Smith, Bowling Green State University, Dept Psychology, Bowling Green, Ohio Hypocretin (or orexin) neurons are located in the hypothalamus and have been implicated in various functions including sleep, arousal and feeding. One area receiving dense hypocretin projections and expressing hypocretin-2 receptors (H-2r) is the medial septum (MS), an area …

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