01q1

Targeting Trends Newsletter 01q1

Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page. Newsletter Highlights Merging of technology makes everyone a winner (page 1-2) Targeted Toxins: Safe, effective in vivo administration (page 5) IB4-Saporin, Neuroscience Antibodies (page 7) [fivecol_one]Page 1Page …

Targeting Trends Newsletter 01q1 Read More »

Targeting Tools: IB4-SAP

IB4, or the B4 lectin isoform from Bandeiraea simplicifolia (Griffonia simplicifolia), has played an important role in the delineation of the pathways of pain transmission. One of the two major groups of primary afferents that target the spinal cord dorsal horn neurons are labeled by IB4; the other group by TrkA and peptides such as …

Targeting Tools: IB4-SAP Read More »

Targeting Topics 01q1

Loss of nerve: a molecular approach to better treatment of chronic pain. Friedrich MJ. JAMA 283(2):187-188, 2000. PMID: 10634324 The use of SP-SAP (Cat. #IT-07) as a promising new method for chronic pain relief is discussed in this review article. Chronic pain has classically been treated in ways that frequently have adverse effects on the …

Targeting Topics 01q1 Read More »

Cover Article: Immunolesioning – From Spinal Cord to Brain

Contributed by Dr. Ann Schreihofer, University of Virginia, contributes this issue’s article from the laboratories of ATS customers. Dr. Schreihofer summarizes her research with anti-DBH-SAP (Cat. #IT-03) to immunolesion specific rostral ventral medulla neurons that project to the spinal cord by injection of anti-DBH-SAP into the rat spinal cord. The toxin is taken up and …

Cover Article: Immunolesioning – From Spinal Cord to Brain Read More »