Melanopsin Rabbit Polyclonal, affinity-purified [AB-N39]

350,00

SKU: AB-N39 Category: Product Size: 50 ug | Antibody Type: affinity-purified, Polyclonal | Host: Rabbit | Reactivity: Mouse | Usage: immunocytochemistry, staining, targeting agent |

Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain melanopsin. The ipRGCs, with their amazing long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Affinity-purified Anti-Melanopsin (UF008) has very high specificity to mouse ipRGCs.

Affinity-purified anti-Melanopsin (UF008) was raised against the 15 N-terminal extracellular amino acids of mouse melanopsin. This antibody does not cross-react with melanopsins of other species, it is very specific for mouse.

2-photon confocal microscope image from a single z-series using AB-N39 in flat-mount mouse retina at 1:4000and an AlexaFluor-568 secondary antibody.  This image is a single optic plane through the ganglion cell layer that also shows some proximal RGC dendrites.
Image courtesy of Matthew Van Hook, Ph.D.

Applications include immunofluorescence (1 µg/ml) and targeting (targeting agent in Melanopsin-SAP, Cat. #IT-44). This antibody works in both cross-section and flat-mount staining.

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

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