Melanopsin Rabbit Polyclonal, affinity-purified [AB-N39]

$350.00

SKU: AB-N39 Category: Product Size: 50 ug | Antibody Type: affinity-purified, Polyclonal | Host: Rabbit | Reactivity: Mouse | Usage: immunocytochemistry, staining, targeting agent |

Description

Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain melanopsin. The ipRGCs, with their amazing long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Affinity-purified Anti-Melanopsin (UF008) has very high specificity to mouse ipRGCs.

Affinity-purified anti-Melanopsin (UF008) was raised against the 15 N-terminal extracellular amino acids of mouse melanopsin. This antibody does not cross-react with melanopsins of other species, it is very specific for mouse.

2-photon confocal microscope image from a single z-series using AB-N39 in flat-mount mouse retina at 1:4000and an AlexaFluor-568 secondary antibody.  This image is a single optic plane through the ganglion cell layer that also shows some proximal RGC dendrites.
Image courtesy of Matthew Van Hook, Ph.D.

Applications include immunofluorescence (1 µg/ml) and targeting (targeting agent in Melanopsin-SAP, Cat. #IT-44). This antibody works in both cross-section and flat-mount staining.

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

View Data Sheet

View Related References

You may also like…