Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain melanopsin. The ipRGCs, with their amazing long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Affinity-purified Anti-Melanopsin (UF008) has very high specificity to mouse ipRGCs.
Affinity-purified anti-Melanopsin (UF008) was raised against the 15 N-terminal extracellular amino acids of mouse melanopsin. This antibody does not cross-react with melanopsins of other species, it is very specific for mouse.
Applications include immunofluorescence (1 µg/ml) and targeting (targeting agent in Melanopsin-SAP, Cat. #IT-44). This antibody works in both cross-section and flat-mount staining.
Images supplied courtesy of Wenjin Xu, Xiarong Lu, and Ignacio Provencio at the University of Virginia.
Image courtesy of Matthew Van Hook, Ph.D.
keywords: Melanopsin, Intrinsically photosensitive retinal ganglion cells, ipRGC, ipRGCs, UF008, Anti-Melanopsin, Anti-UF008
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