Melanopsin Rabbit Polyclonal [AB-N38]


SKU: AB-N38 Category: Antibody Type: Polyclonal | Host: Rabbit | Reactivity: Mouse | Conjugate: unconjugated | Usage: immunofluorescence, staining |

Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain melanopsin. The ipRGCs, with their amazing long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Anti-Melanopsin (UF006) has very high specificity to mouse ipRGCs.

Anti-Melanopsin (UF006) recognizes a sequence representing the 15 most N-terminal amino acids of the mouse melanopsin extracellular domain. Anti-Melanopsin (UF006) does not cross-react with melanopsins of other species, it is very specific for mouse. This antibody is routinely tested by immunofluorescence.

LEGEND: Staining of a cross-sectioned mouse retina. The counter-label in green is PKCalpha, a bipolar cell marker. Anti-Melanopsin staining is in red. Images courtesy of Jingyi Gao, Xiaorong Liu, and Ignacio Provencio.

Applications include immunofluorescence. This antibody works in cross-section staining, but does not work in flat-mount staining. This antibody does NOT work in immunoblotting.

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