Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain melanopsin. The ipRGCs, with their amazing long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Anti-Melanopsin (UF006) has very high specificity to mouse ipRGCs.
Anti-Melanopsin (UF006) recognizes a sequence representing the 15 most N-terminal amino acids of the mouse melanopsin extracellular domain. Anti-Melanopsin (UF006) does not cross-react with melanopsins of other species, it is very specific for mouse. This antibody is routinely tested by immunofluorescence.
Applications include immunofluorescence. This antibody does NOT work in immunoblotting.
keywords: melanopsin, Intrinsically photosensitive retinal ganglion cells, ipRGC, ipRGCs, UF006, Anti-Melanopsin, Anti-UF006, brain, neuroscience, circadian rhythm