CHOp75 Cells 192-IgG-SAP is the #1 rat p75-lesioning tool available for research use. Our development of CHOp75 cells grew from the need for a stable, reliable cell line to use for Quality Control of each new lot of 192-IgG-SAP. Now, these cells are available for use in laboratories worldwide. CHOp75 cells are standard CHO (Chinese […]
Toolbox: Stable Transfected Cell Lines Read More »
The fundamental things apply. “The Peptidergic Control Circuit for Sighing,” recently published in the prestigious journal Nature, has made us rethink our fundamental belief that sighs are only “long, deep breaths expressing sadness, relief or exhaustion.” Often prompting someone to say, “What’s wrong?” As it turns out, sighs “also occur spontaneously every few minutes to
From the President: A Sigh is (Not) Just a Sigh . . . Read More »
by Ronald G. Wiley, M.D., Ph.D., Departments of Neurology and Pharmacology, Vanderbilt University, Nashville, TN and C. J. Vierck, Department of Neuroscience, McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL, USA Degeneration of the cholinergic basal forebrain (CBF: medial septum, diagonal band of Broca, nucleus basalis of Meynert/substantia innominata) is a prominent
A quick update on the pursuit of conditional approval of SP-SAP to treat bone cancer pain in dogs. The FDA has already approved Minor Use/Minor Species (MUMS) designation for the drug, providing extended market exclusivity to treat the >10,000 annual cases of canine bone cancer-related pain, and the ability to commercialize the drug as soon
Veterinary Development of Substance P-Saporin (SP-SAP) Read More »
We are proud to announce the release of our newly redesigned website. It has been crafted to reflect content our customers access most often and to provide new visitors an easier way to learn about ATS’s products and services. Immediately you will notice streamlined menus, simple navigation and access to the information you need, any
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In an effort to accelerate offering new targeted toxins to our customers, we launched the Beta Product program early in 2015. Publications and collaborations are an invaluable source of independent data to support the efficacy of our products. To help streamline this process, we’ve created a catalog of new targeted toxins that we’re offering to
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Proteins come in all shapes and sizes and don’t always contain a ready-to-conjugate binding site. ATS scientists are conjugation experts when it comes to crosslinking peptides, antibodies, and other proteins. Whether you are in need of a Saporin conjugate, biotin labeling, fluorochrome labeling, ADC’s, or other toxin conjugates, we can help you design a strategy
Targeting Tools: Custom Conjugates – Made to Order Read More »
by Kristen Ashley Horner and collaborators R. Murray and M.C. LoganMercer University School of Medicine, Savannah, GA 31404 Repeated exposure to psychostimulants, such as cocaine, can result in patterns of repetitive, inflexible behaviors, known as stereotypy.[1,2] These inflexible behaviors are thought to be similar to the type of behaviors observed with certain psychiatric disorders, such
Read the 2015 Newsletters and recent scientific references 2015, issue 1: Impairments in gait, posture and complex movement control in rats modeling the multi-system, cholinergic-dopaminergic losses in Parkinson’s Disease / by Aaron Kucinski / featuring 192-IgG-SAP (Cat. #IT-01), Anti-ChAT-SAP (Cat. #IT-42) Society for Neuroscience Poster of the Year Award Veterinary Development of Substance P-Saporin (SP-SAP) Targeting Talk:
Targeting Trends 2015 Newsletter Read More »