antibodies

Nattie EE, Li A, Richerson GB, Lappi DA (2004) Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol 556(1):235-253. doi: 10.1113/jphysiol.2003.059766 PMID: 14724193

Summary: The retrotrapezoid nucleus contains neurokinin-1 receptor (NK-1r)-expressing neurons that are involved in chemoreception. NK-1r-expressing neurons are also present in areas that contain medullary serotonergic neurons. These serotonergic neurons have been shown to be chemosensitive in vitro. With two 100-nl injections of 1 µM SP-SAP (Cat. #IT-07), anti-SERT-SAP (Cat. #IT-23), or both, the authors examined whether both cell populations are involved in chemoreception in vivo in rats. The results support that separate populations of serotonergic and NK-1r-expressing neurons are each involved in chemoreception in vivo.

Related Products: SP-SAP (Cat. #IT-07), Anti-SERT-SAP (Cat. #IT-23), Antibody to Serotonin Transporter (SERT, Cat. #AB-N09)

Mnaimneh S, Damaj M, Barhoumi R, Mouneimne Y, Geffard M, Veyret B, Vincendeau P (2004) Evidence for nitric oxide involvement in experimental autoimmune encephalomyelitis and adjuvant-induced arthritis in Lewis rat. The Pain Clinic 16(3):229-243. doi: 10.1163/1568569041798407 PMID: 0

Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)

Angele S, Falconer A, Foster CS, Taniere P, Eeles RA, Hall J (2004) ATM protein overexpression in prostate tumors: possible role in telomere maintenance. Am J Clin Pathol 121(2):231-236. doi: 10.1309/JTKG-GGKU-RFX3-XMGT PMID: 14983937

Related Products: TRF1 Mouse Monoclonal (Cat. #AB-37)

Huang J, Hara Y, Anrather J, Speth RC, Iadecola C, Pickel VM (2003) Angiotensin II subtype 1A (AT1A) receptors in the rat sensory vagal complex: Subcellular localization and association with endogenous angiotensin. Neuroscience 122(1):21-36. doi: 10.1016/s0306-4522(03)00606-7 PMID: 14596846

Objective: To determine interactive sites in the sensory vagal complex of rat brain using dual immunolabeling of antisera recognizing the AT1-AR and Ang II.

Summary: In the rat sensory vagal complex, AT-1A receptors are strategically positioned for involvement in modulation of the postsynaptic excitability and intracrine hormone-like effects of Ang II. In addition, these receptors have distributions consistent with diverse roles in regulation of transmitter release, regional blood flow and/or vascular permeability.

Usage: Immunolabeling (1:200)

Related Products: Angiotensin II receptor (AT-1AR) Rabbit Polyclonal, affinity-purified (Cat. #AB-N25AP), Angiotensin II receptor (AT-1R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N27AP), Angiotensin II receptor (AT-2R) Rabbit Polyclonal, affinity-purified (Cat. #AB-N28AP)

Pagliardini S, Ren J, Greer JJ (2003) Ontogeny of the pre-Bötzinger complex in perinatal rats. J Neurosci 23(29):9575-9584. doi: 10.1523/JNEUROSCI.23-29-09575.2003 PMID: 14573537

Related Products: Antibody to NK-1 Receptor (Cat. #AB-N04)

Alencar JL, Lobysheva I, Chalupsky K, Geffard M, Nepveu F, Stoclet JC, Muller B (2003) S-nitrosating nitric oxide donors induce long-lasting inhibition of contraction in isolated arteries. J Pharmacol Exp Ther 307(1):152-159. doi: 10.1124/jpet.103.052605 PMID: 12954813

Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)

Moller LN, Stidsen CE, Hartmann B, Holst JJ (2003) Somatostatin receptors. Biochim Biophys Acta 1616(1):1-84. doi: 10.1016/s0005-2736(03)00235-9 PMID: 14507421

Related Products: Somatostatin Receptor-1 (SSTR1) Mouse Monoclonal (Cat. #AB-N35), Somatostatin Receptor-1 (SSTR1) Rabbit Polyclonal (Cat. #AB-N20), Somatostatin Receptor-5 (SSTR5) Mouse Monoclonal (Cat. #AB-N24)

Alencar JL, Lobysheva I, Geffard M, Sarr M, Schott C, Schini-Kerth VB, Nepveu F, Stoclet JC, Muller B (2003) Role of S-nitrosation of cysteine residues in long-lasting inhibitory effect of nitric oxide on arterial tone. Mol Pharmacol 63(5):1148-1158. doi: 10.1124/mol.63.5.1148 PMID: 12695543

Related Products: NO-L-Cysteine Mouse Monoclonal, Conjugated (Cat. #AB-T125)

Kennedy AD, Solga MD, Schuman TA, Chi AW, Lindorfer MA, Sutherland WM, Foley PL, Taylor RP (2003) An anti-C3b(i) mAb enhances complement activation, C3b(i) deposition, and killing of CD20+ cells by rituximab. Blood 101(3):1071-1079. doi: 10.1182/blood-2002-03-0876 PMID: 12393727

Related Products: Antibody to Complement C3 (3E7) (Cat. #AB-V82)

Panda S, Sato TK, Castrucci AM, Rollag MD, DeGrip WJ, Hogenesch JB, Provencio I, Kay SA (2002) Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science 298(5601):2213-2216. doi: 10.1126/science.1076848 PMID: 12481141

Objective: To investigate the role of melanopsin in circadian photoentrainment in mammals.

Summary: The study focused on understanding how melanopsin, an opsin-based photopigment, affects the circadian rhythms in mammals. By generating melanopsin-null mice and observing their response to light-induced circadian phase shifting, the research demonstrated that while these mice maintain some entrainment to light/dark cycles, their phase resetting in response to monochromatic light is severely attenuated. This highlights melanopsin’s critical role in circadian photoentrainment, alongside other mechanisms that contribute to this process.

Usage: Anti-Melanopsin (AB-N38) was incubated with tissue for 24 hr at 4°C at a 1:2,500 dilution in a TBS incubating buffer containing 1% bovine serum albumin, 0.25% carrageenan lambda and 0.003% Triton X-100.

Related Products: Melanopsin Rabbit Polyclonal (Cat. #AB-N38), Melanopsin Rabbit Polyclonal, affinity-purified (Cat. #AB-N39)