Author name: Kristen Hartman

Lifespan and cholinergic changes in cognitive flexibility in rats

Cammarata C, DeRosa ED, Anderson AK (2018) Lifespan and cholinergic changes in cognitive flexibility in rats. Neuroscience 2018 Abstracts 512.05 / GGG8. Society for Neuroscience, San Diego, CA. Summary: The ability to update one’s mental schemas in order respond flexibly and adaptably – i.e. cognitive flexibility – is crucial to navigating a dynamic environment. Proactive […]

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SUVN-G3031, H3 receptor inverse agonist produces wake promoting activity in rats with hypocretin-2-saporin lesions of the lateral hypothalamus

Daripelli S, Bhayrapuneni G, Tirumalesetty C, Benade V, Subramanian R, Petlu S, Praveena N, Jayarajan P, Shinde A, Badange R, Bhatta V, Nirogi R (2018) SUVN-G3031, H3 receptor inverse agonist produces wake promoting activity in rats with hypocretin-2-saporin lesions of the lateral hypothalamus. Neuroscience 2018 Abstracts 679.23 / VV4. Society for Neuroscience, San Diego, CA.

SUVN-G3031, H3 receptor inverse agonist produces wake promoting activity in rats with hypocretin-2-saporin lesions of the lateral hypothalamus Read More »

Exercise is neuroprotective following partial motoneuron depletion: Run for your dendrites

Chew C, Sengelaub DR (2018) Exercise is neuroprotective following partial motoneuron depletion: Run for your dendrites. Neuroscience 2018 Abstracts 761.02 / MM11. Society for Neuroscience, San Diego, CA. Summary: We have previously demonstrated that partial depletion of motoneurons innervating the quadriceps muscles induces dendritic atrophy in remaining motoneurons. Furthermore, systemic treatment with supplemental androgens is

Exercise is neuroprotective following partial motoneuron depletion: Run for your dendrites Read More »

Screening targeting agents and their cell surface biomarkers for high specificity and rapid internalization via cell death and fluorescence

Ancheta L, Bouajram R, Lappi DA (2018) Screening targeting agents and their cell surface biomarkers for high specificity and rapid internalization via cell death and fluorescence. Neuroscience 2018 Abstracts 128.20 / M17. Society for Neuroscience, San Diego, CA. Summary: Some of the most recent successes in the treatment of cancers or research into passive immunotherapies

Screening targeting agents and their cell surface biomarkers for high specificity and rapid internalization via cell death and fluorescence Read More »

Interaction between the retrotrapezoid nucleus and the parafacial respiratory group to regulate active expiration and sympathetic activity in rats

Zoccal DB, Silva JN, Barnett WH, Lemes EV, Falquetto B, Colombari E, Molkov YI, Moreira TS, Takakura AC (2018) Interaction between the retrotrapezoid nucleus and the parafacial respiratory group to regulate active expiration and sympathetic activity in rats. Am J Physiol Lung Cell Mol Physiol 315(5):L891-L909. doi: 10.1152/ajplung.00011.2018 Objective: To investigate the microcircuitry responsible for

Interaction between the retrotrapezoid nucleus and the parafacial respiratory group to regulate active expiration and sympathetic activity in rats Read More »

NGF p75 antibody for brain research

Targeting Topics /

Two more publications this week using an ATS exclusive antibody: NGFR (mu p75) Antibody (Cat. #AB-N01) Nicotinamide Mononucleotide Adenylyltransferase 2 maintains neuronal structural integrity through the maintenance of Golgi structure. Pottorf T, Mann A, Fross S, Mansel C, & Vohra BPS. (2018). Neurochem Intl Objective:  investigated the link between NMNAT2 loss, Golgi fragmentation and axon

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Removal of p75 neurotrophin receptor expression from cholinergic basal forebrain neurons reduces amyloid-β plaque deposition and cognitive impairment in aged APP/PS1 mice.

Qian L, Milne MR, Shepheard S, Rogers ML, Medeiros R, Coulson EJ (2019) Removal of p75 neurotrophin receptor expression from cholinergic basal forebrain neurons reduces amyloid-β plaque deposition and cognitive impairment in aged APP/PS1 mice. Mol Neurobiol 56(7):4639-4652. doi: 10.1007/s12035-018-1404-2 Objective: To investigate the contribution of CBF neuronal p75NTR to the progression of Alzheimer’s Disease

Removal of p75 neurotrophin receptor expression from cholinergic basal forebrain neurons reduces amyloid-β plaque deposition and cognitive impairment in aged APP/PS1 mice. Read More »

DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members

Garrett AM, Khalil A, Walton DO, Burgess RW (2018) DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members. Proc Natl Acad Sci U S A 115:E10216-E10224. doi: 10.1073/pnas.1809430115 Summary: Focus on DSCAM (Down syndrome cell adhesion molecule 1) self-avoidance function in the mouse retina. DSCAM and members of

DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members Read More »

New Publications – Retinal Ganglion Cells and Cerebellar Purkinje Cells

Targeting Topics /

Two publications out this week using ATS antibodies: Anti-Melanopsin (Cat. #AB-N38) and Anti-Metabotropic Glutamate Receptor 2 (mGluR2; Cat. #AB-N32) Sabbah S, Papendorp C, Koplas E, Beltoja M, Etebari C, Gunesch AN, Carrete L, Kim MT, Manoff G, Bhatia-Lin A, Zhao T, Schreck D, Dowling H, Briggman KL, Berson DM (2018) Synaptic circuits for irradiance coding

New Publications – Retinal Ganglion Cells and Cerebellar Purkinje Cells Read More »

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